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Pharmaceutics > Aural Route > Flashcards

Aural Route Flashcards

1
Q

What are the drug treatments for aural?

A 
Antibiotics
Anti-inflammatories
Antiseptics
Cleansing solutions (less common now)
Wax softeners
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2
Q

What are the dosage forms?

A

Drops
Sprays
Washes

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3
Q

Describe ear drops

A

Topically

Either in solution or suspension in suitable vehicle

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4
Q

What is cons of ear drops?

A

Some vehicles (eg. Alcohol) may cause stinging
Oil based preparations may need to be pre-warmed
Products can contain oil - eg. peanut oil

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5
Q

Why do oil preparations need to be pre-warmed?

A

Increase effectiveness

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6
Q

Describe ear wax

A

Normal body secretion

Mostly lipophilic

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7
Q

What is the function of ear wax?

A

Provides protective film on meatal skin

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8
Q

When is ear wax removed?

A

Only if causes deafness or interferes with view of ear drum

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9
Q

What do cerumenolytics do?

A

Soften cerumen + lubricate canal = facilitate ear wax remove from ear canal

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10
Q

What are examples of cerumenolytics?

A

Olive or almond oil drops

Sodium bicarbonate ear drops

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11
Q

What is otitis externa?

A

Inflammatory reaction of meatal skin caused by bacteria or fungus

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12
Q

How can otitis externa be treated?

A

Many cases recover after cleansing by suction or dry mopping

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13
Q

What can be used if otitis externa permits?

A

Corticosteroids ear drops
Astringent solution
Acetic acid solution

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14
Q

What are astringent preparations?

A

Substances that cause shrinking or construction of body tissues

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15
Q

How are astringent preparations applied?

A

Locally after topical medicinal application

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16
Q

What is an example of an astringent preparation?

A

Aluminium acetate ear drops (13%)

17
Q

Describe corticosteroid preparations

A

Formulated in combo with anti-infective drugs

18
Q

What is an example of corticosteroid preparation?

A

Otomize ear spray

19
Q

What does acetic acid preparation treat?

A

2% locally

Otitis externa

20
Q

What are the activities of acetic acid preparations?

A

Antibacterial + antifungal

21
Q

What are acetic acid preparations active against?

A

Haemophilus + pseudomonas species

Candida + trichomonas

22
Q

What is the shelf life of acetic acid preparations?

A

18 months

23
Q

But what is acetic acid preparation’s shelf life once opened?

A

1 month

Pharmaceutics (21 decks)

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