Asthma - Adults and Kids Flashcards

1
Q

what is the definition of asthma (3)

A

increased responsiveness of airway by stimuli

wide spread narrowing - changes in severity

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2
Q

what are the symptoms of asthma (in adults) (5)

A

expiratory wheeze
dry cough
chest tightness (central = cardiac, peripheral = respiratory)
dyspnoea (S.O.B)

expiration difficulties

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3
Q

what is the scale of acute asthma attacks - what else should you keep in mind when dealing with patents in these attacks

A

moderate, severe, life threatening, near fatal

that life threatening attack might not cause distress

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4
Q

what is asthmas mechanism of attack

A

airway inflammation by immune system

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5
Q

what is the prevalence of asthma in adults

A

5-10% of adults (most chronic UK condition)

it adulthood it effects females at a greater rate than males

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6
Q

what dose airway inflammation lead to (2)

A

widespread narrowing of airways

or increase airway reactivity

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7
Q

what does increased airway reactivity lead to (2)

A

spontaneous airway narrowing

airway narrowing by a stimuli

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8
Q

what is the difference between a normal airway and asthmatic airway

A

asthmatic airway has is thicker and chronically inflamed

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9
Q

what happens to a asthmatic airway during a attack

A

the relaxed smooth muscle tightens and traps air in the alveoli

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10
Q

what are the 3 proven risk factors for asthma

A

inherited genes
maternal smoking
occupation

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11
Q

what is atopy

A

an inherited predispostiton

produce IgE when exposed to environmental allergens

leads to hightend immune response

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12
Q

what is atopy

A

an inherited predisposition

produce IgE when exposed to environmental allergens

leads to heightened immune response

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13
Q

if first degree family memebers have asthma or another atopic disease what happens

A

the risk of you getting asthma increases

especially if mum has it (3X more likely compared to dad)

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14
Q

if first degree family members have asthma or another atopic disease what happens

A

the risk of you getting asthma increases

especially if mum has it (3X more likely compared to dad)

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15
Q

what dose maternal smoking cause in the child

A

higher risk of asthma

higher risk of attack due to higher airway responsiveness

child has reduced FEV1

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16
Q

what is the grandmother effect - what phenomenon is this

A

grandma smokes (on maternal side, more likely to get asthma)

epigenetic = hereditary trait that doesn’t relate to a change in DNA sequence

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17
Q

how much asthma is caused by occupation

A

10-15% of adult onset asthma

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18
Q

what are some examples of occupations at higher risk of asthma

A

backers , painters

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19
Q

what is the most important thing about making a asthma diagnosis

A

HISTORY!!!!

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20
Q

what relating to the symptoms of asthma can lead to a more likely diagnosis

A

variation of symptoms depending on time/season/work or weekend

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21
Q

asthma also has triggers what are some of them

A
exercise 
URTI - rhinovirus
cold air 
cigarette smoke 
pets 
drugs
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22
Q

what drugs act as asthma triggers (2)

A

Beta blockers

aspirin

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23
Q

it wont be asthma if there is (3)

A

clubbing
stridor (something blocking the airway, pos. aspiration)
asymmetric expansion

24
Q

what is asthma an example of

A

a obstructive disease

obstructs airflow

25
what tests are done to diagnoses asthma
spirometry peak flow monitoring CO gas transfer test response to bronchodilator - beta2 agonist
26
what spirometry value is expected from asthma
FEC1/FVC = less than 70%
27
why is a peak flow test used
to determine if there is variability in airflow obstruction
28
what are the symptoms of a moderate attack
mildly greater symptoms than normal | PEF 50-75%
29
what are the symptoms of a sever attack
anyone cant complete full sentences in 1 breath HR over 110bpm RR over 25 breaths per minute PEF = 22-50% of predicted
30
what are the symptoms of a life threatening attack
grunting impaired consciousness, confusion silent chest o2 saturation is lower than 92 PaO is lower than 60mmHg
31
what are the symptoms of a near fatal asthma attack
raised PaCO2 need for mechanical ventilation
32
what two drugs cause reversibility in asthma
beta2 agonists | corticosteroids
33
what is the Co gas transfer test used for
distinguishing between asthma and COPD
34
how dose the CO gas transfer test work
Co is passed on the Hb this is reduced in COPD and increased in asthma
35
what is the one thing to remember with asthma - NO..
no wheeze no asthma
36
what are the similarities of adult asthma with children's asthma (5)
its common symptoms are the same triggers, treatment and pathology are also all the same
37
what is the prevalence of asthma in children (2)
prevalence 0-15% more boys than girls have asthma
38
what are the multiple hits that lead to asthma
genes inherited abnormal lungs early onset atopy later exposures (rhinovirus, exercise, smoking0
39
why is rhinovirus a trigger
as asthma as a unusual response to infection due to the already inflamed airway
40
how can you tell there is a wheeze - is this different in kids
the wheeze is musical kids airway narrower so more likely to be musical
41
what is a differential diagnosis for a child that has a wheeze how would you diagnose
VIW - viral induced wheeze as asthma is a dimmer switch of symptoms VIW is a light switch - on/off when have a virus
42
what treatment is given for VIW
salbutamol
43
how do you confirm a asthma diagnosis
trial of inhaled cortical steroids
44
is there a asthma test for children
no
45
is there a lower age limit for diagnosis
no
46
what are ICS (inhaled cortical steroids) good for in peads
diagnostic as a regular preventer very safe
47
what should be added to a paediatric therapy routine if needing regular preventer (step 2)
add a beta 2 agonist
48
what are the adverse effects of ICS in peads
height suppression
49
what is step 3 in a peads asthma therapy
add LABA
50
what must you do for peads when giving the LABA for step 3
do not use without ICS use as a fixed dose inhaler
51
what must kids used when using a pMDI
always use a spacer
52
what is the preferred method of treatment of peads asthma
pMDI with spacer
53
what other non medical management should be tried for kids asthma
stop smoking exposure remove environmental triggers
54
what are the best treatment for step 1
SABA
55
how should steroids be delivered in acute asthma settings
oral steroids
56
how should steroids be delivered in chronic asthma settings
inhaled steroids
57
what is important about childhood asthma compared to adult asthma
its very steroid sensitive