ASO

Question 1

● Bacteria commonly found in the throat, pharynx, and skin
● The known bacteria is…

Answer 1

GROUP A Streptococcus

Streptococcus pyogene

Question 2

● The majority of GAS Infections are only mild illnesses, such as_____ and _____

● If left untreated, the bacteria may migrate to the organs, causing a devastating damage leading to
IRREVERSIBLE KIDNEY FAILURE and other LIFE THREATENING DISEASES

Answer 2

IMPETIGO and STREP THROAT

Question 3

Mediates cell attachment

Answer 3

Protein F

Question 4

Inhibits phagocytosis
Masks antigen
Prevents opsonization

Answer 4

Hyaluronic acid

Question 5

Major virulence factor

Answer 5

Protein M

Question 6

Similar structure to heart and kidneys

Answer 6

M protein

Question 7

Antiphagocytic
- Produces several enzymes
and hemolysins that contributes to tissue invasion and destruction, including Streptolysin O, Streptolysin
S, Streptokinase, DNAse, and
Hyaluronidase

Answer 7

M protein

Question 8

Easily degraded

First to appear in infection

Answer 8

Anti DNAse

Question 9

Mediate production of rash (Scarlet
fever) or multisystem effects that can
cause death.

Answer 9

Streptococcus pyogenic endotoxins

Question 10

Destroys complement chemotactic
factors

Answer 10

C5A peptidase

Question 11

Sequelae

Answer 11

Rheumatic fever
Glomerulonephritis