ASCP Practice Test Review Qs

Question 1

Massive transfusion event complications?

Answer 1

Hypocalcemia due to binding of calcium (citrate chelates calcium)

hypothermia

tingling feeling

citrate toxicity

Question 2

method for determining accurate phenotypes in transfused patients?

Answer 2

density separations

Question 3

Hypotonic wash

Answer 3

for separating Hgb SS from Hgb A

Question 4

Thiol reagents

Answer 4

differentiate IgM from IgG antibodies

Question 5

at room temperature, why does urine pH increase with bacteria?

Answer 5

production of urease

Question 6

what kind of urine is calcium oxalate found in?

Answer 6

neutral or acidic

Question 7

why would a urine sample look cloudy after someone recently ate? (reagent strip results are all normal)

Answer 7

alkaline tide effect, amorphous phosphates increase turbidity and alkaline urine

Question 8

Bessey-Lowry-Brock method for alkaline phosphatase activty uses what substrate?

Answer 8

para-nitrophenylphosphate

Question 9

why does blood for digoxin assays need to be collected between 8 or more hours after drug administration?

Answer 9

tissue and serum levels need to reach an equilibrium

Question 10

post exercise samples would have what results in the blood?

Answer 10

elevated lactic acid and elevated pyruvate due to increased carb metabolism

Question 11

biologically active precursor of a fat soluble vitamin?

Answer 11

retinol is one of the three biologically active forms of fat soluble vitamin A

Question 12

total granulocyte count greater than 7.5 x 10^3?

Answer 12

absolute neutrophilic leukocytosis

Question 13

what % minimum is required to be diagnostic for PLL? (Prolymph leukemia?)

Answer 13

> 55%

Question 14

high wbc
low rbc
low hgb
increased mvc
increased mchc

Answer 14

warm the specimen and recount

Question 15

one of the coagulation tests that correlates with pt mortality with Sars Cov 2 was?

Answer 15

D-dimer

Question 16

VwF mediates plt adhesion by binding to the platelet receptor?

Answer 16

GpIb/GP IX/GP V

Question 17

most common cause of anemia in hospitalized patients?

Answer 17

anemia of chronic inflammation
assocaited with infections and malignant conditions

Question 18

most common humoral immune deficiency disease?

Answer 18

selective IgA deficiency

Question 19

when a nk cell comes in contact with a cell expressing MCH I, what happens?

Answer 19

inhibition of killing since that would be a healthy cell

Question 20

anti-nuclear antibody test with a titer of 1:320 with a peripheral pattern?

Answer 20

anti-dsDNA 1:80 high titer antibodies to Sm

Question 21

Live attenuated vaccine used for human immunization?

Answer 21

measles

Question 22

what component of compliment is associated with chemotactic activity?

Answer 22

C5a is chemotaxin for neuts, basos, mast and monos

Question 23

anaerobic bacteria acceptable specimen?

Answer 23

suprapubic bladder aspiration

Question 24

Enterobacteriaceales share what characteristics?

Answer 24

reduce nitrate to nitrite

Question 25

what may indicate a blood culture bottle is a contaminant?

Answer 25

1 bottle of 1 set is positive
no positive results until day 5 of incubation

Question 26

what organism can you use for positive control for lecithinase on egg yolk agar?

Answer 26

C perfringens

Question 27

antibiotic used to kill or supress fungi in media

Answer 27

cycloheximide

Question 28

plasmodium sporoziote proliferation site?

Answer 28

liver

Question 29

definitive ID of neisseria gonorrhoeae ?

Answer 29

utilization of carbs

Question 30

what species produces cladosporium, phialophora and fonsecasea? crust like cauliflower lesion and slow growing black mold

Answer 30

fonsecaea pedrosoi

Question 31

POCT benefits?

Answer 31

faster turn around time

Question 32

potential carcinogen chemical?

Answer 32

formaldehyde

Question 33

flow cytometer method?

Answer 33

immunofluorescence

Question 34

pulse field gel electrophoresis

Answer 34

epidemiological typing of bacterial strains

Question 35

specificity

Answer 35

true negative results, negativity in absence of a disease