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Arthritis Flashcards

1
Q

Arthritis

A

Inflammation of joint

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2
Q

Types of arthritis

A
  1. Degenerative
  2. Immune mediated
  3. Metabolic
  4. Infectious
  5. Neoplastic
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3
Q

___ major source of morbidity

A

Osteoarthritis

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4
Q

Types of osteoarthritis

A

OA

DJD

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5
Q

MC joint disorder

A

Osteoarthritis

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6
Q

Advanced osteoarthritis can cause

A

Inflammation and subchondral changes

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7
Q

___ have limited growth capacity

A

Chondroctyes

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8
Q

MC form OA

A

Primary

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9
Q

Secondary OA due to

A

Previous injury or deformity

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10
Q

Common locations for OA

A

Cervical and lumbar spine
DIP joints
1st MCP joint
1st TMT joint

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11
Q

Least likely to cause ankylosis

A

OA

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12
Q

____ Patients have clinically significant inflammation

A

50%

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13
Q

____ and ____ seen with advanced OA

A

Inflammation

Subchondral cyst

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14
Q

Joint mice

A

Free fragment of bone causing pain

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15
Q

Risk factors for OA

A 
>50 yo
Genetics
Estrogen
High bone density 
Mechanical stress
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16
Q

Osteophytes ____ impinge nerve roots

A

Rarely

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17
Q

____ at DIP joints observed in OA

A

Heberden’s nodes

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18
Q

RA is ___ Disease and is chronic and ___

A

Autoimmune

Systemic

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19
Q

___ present in 80% RA cases

A

Rheumatoid factor

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20
Q

___ present in 70% RA

A

Anti-cyclic citrullinated peptides

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21
Q

Signs of RA

A 
Weakness
Malaise 
Fever
Decrease ROM
Cachexia
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22
Q

RA MC affects

A

Small joints

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23
Q

____ observed in 30% of RA

A

Atlanto-axial instability

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24
Q

Pannus in RA can cause

A

Ulnar deviation

Swan-neck deformity

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25
Age for RA
Age 35-50
26
Sex more likely to get RA
Females 3-5X
27
Felty Syndrome combo of
RA Neutropenia Splenomegaly
28
Felty Syndrome MC in
Elderly females
29
Caplan Syndrome combo of
RA | Pneumoconiosis
30
Caplan Syndrome can mimic
Asthma
31
Juvenile RA
Autoimmunity of mult tissues
32
Juvenile RA affects what part of body
Large joints | Knee, hip
33
JRA MC in
Females
34
Biphasic age of JRA
MC 1-3 yo 6-13 yo
35
Still’s disease
JRA + spiking fever, rash, pericarditis
36
JRA is ___ for RF
Negative
37
Scheuermann’s Disease aka
Juvenile kyphosis
38
Diagnosis for scheuermann’s Disease
Wedge shaped vertebrae > 3 consecutive > 5 degree angle
39
Scheuermann’s Disease MC in
Adolescent males
40
Symptoms of scheuermann’s
Excesses T kyphosis Schmorl’s nodes (end plate herniation up into vertebral body) Aching pain worse with activity
41
Seronegative spondyloarthropathies
Autoimmune attack (PEAR)
42
PEAR
Psoriatic arthritis Enteropathic arthritis Ankylosing spondylitis Reactive arthritis
43
Enterophathic arthritis associated with
Crohn’s | UC
44
Ankylosing spondylitis associated with
Inflammation Sacroiliitis Syndesmophytes Ankylosis of SI joint
45
AS MC in
Males
46
Radiographic findings associated with advanced Ankylosing spondylitis
``` Syndesmophytes Bamboo spine Trolly track sign Ankylosis of SI joint Ankylosis of L spine Dagger sign Hypolordosis of L spine Squaring of V bodies ```
47
Rhyme for reactive arthritis
Can’t see Can’t pee Can’t climb tree
48
Can’t see for Reactive arthritis refers to
Conjunctivitis | Uveitis
49
Can’t pee of reactive arthritis refers to
Urethritis Cervicitis Diarrhea
50
Can’t climb tree of reactive arthritis refers to
Arthritis in large joints (esp Achilles’ tendon)
51
Reactive arthritis is ____ and associated with ____
Autoimmune Infection
52
Infections that can trigger reactive arthritis
GI: salmonella, shigella GU: gonorrhea, chlamydia
53
Reactive arthritis MC in
Males 20-40
54
Polymyalgia rheumatica (PMR) aka
Idiopathic chronic inflammation
55
Symptoms of PMR
Prolonged morning stiffness Shoulder pain Hip pain
56
PMR MC in
Females > 50 yo Northern Europeans
57
PMR associated with
Giant cell arteritis
58
Treatment for PMR
Corticosteroids
59
Primary gout
Abnormal purine metabolism | MC
60
Secondary gout
After disease or medication
61
Chronic topheaceous gout
``` Erosion of joint and loss of joint space Gouty nephropathy (20% lethal) ```
62
Symptoms of gout
Tissues red, swollen, warm, painful
63
Gout MC to affect
MTP joint of Hallux
64
Gout involves _____ accumulating
Uric acid/ monosodium urate crystals

Systems Path 1 (12 decks)

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