Arboviruses Flashcards
Enzootic
use mammals or birds as natural hosts, humans may be a dead end
Name four main viral families of arboviruses.
Family: Togaviridae Genus: Flavivirus G: Alphavirus F: Bunyavirus G: Bunyavirus G: Phlebovirus
Name diseases in T. Flavivirus.
~ Dengue
~ Yellow fever
~ Japanese encephalitis
~ West Nile fever
Name diseases in T. Alphavirus.
Chikungunya
Name diseases in B. Bunyavirus.
LaCrosse virus
Name diseases in B. Phlebovirus.
Rift Valley Fever
Extrinsic incubation period
time between blood-feeding and transmission - varies with virus, temp, mosquito
generally 8-14 days
Transovarial transmission
transmission from female mosquito to eggs, offspring effected, v rare
Arthralgia
joint pain
E glycoprotein
associated with receptor binding, antibody response, haemagglutination
(dengue)
E&M proteins
span lipid envelope, form outer protective later
dengue
7N (non-structural) proteins
associated with viral replication and assembly
dengue
Dengue
…
Diapause
period of suspended development in an insect, especially during unfavourable environmental conditions
Yellow fever
Zoonosis 3 cycles: ~ Jungle (Aedes africanus + monkeys) ~ Urban (Aedes aegypti + Human) ~ Savannah/Intermediate (Aedes spp. and non-human/human primate_
Japanese encephalitis
~ zoonosis
~ Culex mosquitoes
~ herons/egrets are maintain hosts
~ pig amplifying hosts
West Nile Virus
Enzootic
~ cycle between passeriform birds and Culex mosquitoes
~ spillover transmission to humans and equids (dead ends)
Chikungunya
~ zoonosis + emerging alphavirus
~ cycles between monkeys, birds, cattle + rodents
Rift Valley Fever
Zoonosis
~ domestic livestock and over 30 mosquito spp. incl. Aedes, Culex + Anopheles
Zika
~ transmitted by Aedes aegypti
~ occurs in wild and urban areas
Haemolymph
mosquito body cavity
