APRV Flashcards

1
Q

What are the advantages of APRV?

A
  • uses lower peak and mean airway pressures
  • increases cardiac index
  • decreases central venous pressure
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2
Q

What is the open lung approach?

A

high peep, low lung pressure

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3
Q

What is the best mode to help limit lung damage?

A

low volume settings adjusted to maintain plateau pressures between 25-30 cmH2O simulating PCV

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4
Q

What are some lung protective strategies?

A
  • ALI and ARDS
  • keep plateau pressures <30 cmH2O
  • low tidal volume ventilation (4-6 mL/kg)
  • peep to restore FRC
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5
Q

What are the current strategies for ventilating between upper and lower inflection points?

A
  • increase MAP while limiting peak alveolar pressure
  • preventing alveolar collapse by ventilating above the lower inflection point
  • preventing over distention by ventilating below the upper inflection point
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6
Q

What is BiLevel in comparison to APRV?

A

a form of pressure ventilation designed to embrace dual peep levels and inspiratory/expiratory times that allow traditional PC-like breath delivery to APRV-like breath delivery

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7
Q

What are the four main settings in APRV?

A

P-high
P-low
T-high
T-low

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8
Q

P-high and P-low are specific independent settings, therefore what happens to P-high when you raise P-low?

A

does not change

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9
Q

If your P-low is set to 5 and you P-high is set to 15, what is your set PS?

A

15 cmH2O

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10
Q

If your P-low is set to 5, your P-high is set to 15 and your PS is 15, what are all spontaneous breaths at P-high supported by??

A

5 cmH2O

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11
Q

How does bilevel look similar to PCV-SIMV?

A

by setting P-high, T-high and frequency close to typical ventilation settings

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12
Q

What are the clinical advantages to spontaneous breathing at 2 peep levels?

A
  • a potential decrease in sedation (sedation due to patient/ventilator dyssynchrony may be kept at a lower level)
  • less sedation could result in: less interaction with other organ function, patients can be mobilized easier, an active cough may improve secretion removal, inability to identify complications that can be masked by sedation
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13
Q

How does spontaneous breathing ventilation differ from paralyzed patients?

A

it provides ventilation to dependent lung regions which get the best blood flow

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14
Q

How does paralyzed ventilation differ from spontaneous breathing?

A

during PPV for paralyzed patients, the anterior diaphragm is displaced towards the abdomen with the non-dependent regions of the lung receiving the most ventilation where the perfusion is the least

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15
Q

Is there mechanical breathing in APRV?

A

no

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16
Q

What is APRV?

A

utilizes very short expiratory time. this short time at a low pressure allows for exchange of gas

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17
Q

What is the critical setting in APRV?

A

T-low

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18
Q

How is T-high used in APRV?

A

it varies with frequency changes and merely determines the interval that the lungs are held at P-high

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19
Q

When should you consider APRV?

A
  • bilateral infiltrates
  • p/f ratio <300 and falling
  • plateau pressure
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20
Q

What are the goals with APRV? (first five)

A
  • to prove LPV supported by the ARDSnet research
  • minimize alveolar over distension
  • avoid repeated alveolar collapse and reexpansion
  • restore FRC through recruitment and maintain FRC by creating intrinsic peep
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21
Q

What are the goals with APRV? (last five)

A
  • lower FIO2
  • protect lungs
  • make patient comfortable
  • use less sedation
  • wean patient off the ventilator
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22
Q

What are the three types of lung units in ARDS pattern?

A
  • normal region (primarily non-dependent area)
  • consolidated, edematous, atelectatic region (dependent area)
  • region that is collapsed during exhalation and recruitable during inspiration
23
Q

What are the clinical advantages to spontaneous breathing in ARDS during APRV?

A
  • APRV with spontaneous breathing showed a decrease in V/Q mismatch that increased over time
  • spontaneous breaths in APRV as small as 70-150 mL in adults improved oxygenation and CO2 removal
24
Q

What are the similarities of APRV to high frequency ventilation?

A
  • both hold lungs at near constant lung MAP, limiting pressure swings
  • both shown to be effective in decreasing dead space, improving gas exchange, increasing cardiac output
  • APRV is accomplished with a conventional ventilator, a conventional circuit and is less technically challenging
25
Q

What is high frequency ventilation?

A

breathing in and out at the same time. like filling a glass all the way and still put in water so it over flows

26
Q

Who are poor candidates for APRV?

A
  • patients with increase RAW
  • patients who are unable to empty their lungs in 2 seconds
  • asthma and COPD patients
27
Q

What is a reliable indicator that tells if a patient is a poor candidate for APRV?

A

examine their expiratory flow pattern to determine increased resistance

28
Q

What are the APRV clinical guidelines?

A
  • APRV has been suggested for restrictive patients only (obstructive easily develop air trapping)
  • start early with CPAP and switch to APRV as CO2 clearance and/or decreased work of breathing is desired
29
Q

How do you set up APRV?

A
  • P-high: set so plat is not above 30
  • P-low: 0
  • T-high: start at 5
  • T-low: start at 0.5
30
Q

Initial settings of P-high

A

typically about 20-25, however in patients with play at or above 30, set at 30 (in desperation can go to 35)

31
Q

What are the exceptions to setting really high P-high settings?

A
  • morbid obesity

- decreased thoracic or abdominal compliance

32
Q

What should you set P-low to and why?

A

zero because it creates the greatest pressure gradient and fast expiratory flows

33
Q

What is T-high and how should you set it?

A

the inspiratory time that is set to a minimum of 5 seconds, and is progressively increased. do NOT use rate of over 15. its target is oxygenation

34
Q

Establishing T-low

A

do not want to let exhalation go to complete emptying and regional auto-peep is desirable outcome

35
Q

How would you set T-low?

A

set time low so that expiratory flow from patient ends at about 75-50% of peak expiratory flow OR one time constant (i.e, if peak expiratory flow is 80 L/min, then “dump” should end when flow is between 60-40 L/min

36
Q

How would you improve oxygenation with APRV?

A
  • reduce sedation
  • re-assess peep (move towards 75%)
  • decrease T-low
  • increase P-high, T-high, FIO2
37
Q

What should you NOT do if a patient has a high CO2?

A

increase T-high

38
Q

What should you do if your patient has PaO2 that is too low?

A

decrease T-low

39
Q

What should be your goal for all oxygenation choices?

A

increase MAP

40
Q

How could you improve CO2?

A
  • reduce sedation
  • upper pressure is adjusted to maintain dec WOB or O2 delivery goals
  • increase T-low and PS of spontaneous breaths
  • decrease T-high
41
Q

What are you doing when you increase P-high?

A

increasing the pressure gradient which increases flow

42
Q

What should you do to decrease CO2?

A
  • decrease T-high
  • increase P-high to increase change in pressure and volume exchange
  • check T-low and increase if possible
43
Q

What should you do to increase CO2?

A
  • increase T-high
  • decrease P-high to decrease change in pressure
  • it may be better to accept hypercapnia than to reduce P-high so much that oxygenation decreases
44
Q

What are the disadvantages of APRV?

A
  • potential for alveolar de-recruitment during the pressure release
  • APRV is affected by changes in lung compliance
  • if release phase is not synchronous with patient’s effort, discomfort may result
45
Q

What patients should you be cautious with using APRV?

A
  • patients that have COPD, asthma or any other type of air trapping disease
  • barotrauma could be a side effect
46
Q

What are the overall advantages?

A
  • spontaneous breathing
  • maintains peak airway pressures at CPAP levels (over distention minizmed)
  • continuous lung recruitment maneuver
47
Q

What should you accomplish before weaning from APRV?

A
  • FIO2 40-50%
  • reduce P-high by 2 until it is below 20
  • increase T-high to change vent set rate by 5 releases/time
48
Q

What is DROP and DRAG?

A

DROP- drop P-high in increments of 1-3 (usually about 2)
DRAG- increase T-high
^do the above until it looks just like CPAP

49
Q

For a P/F ratio of greater than or equal to 300, what should your estimated MAP requirements be?

A

10-15 cmH2O

50
Q

For a P/F ratio of greater than or equal to 250, what should your estimated MAP requirements be?

A

15-20 cmH2O

51
Q

For a P/F ratio of greater than 200, what should your estimated MAP requirements be?

A

20-25 cmH2O

52
Q

For a P/F ratio of greater than 150, what should your estimated MAP requirements be?

A

25-30 cmH2O

53
Q

For a P/F ratio of greater than 100, what should your estimated MAP requirements be?

A

30-35 cmH2O