April 27 Flashcards
What are the components released from mast cells when they bind the Fc portion of IgE mediating allergic reaction in local tissue?
Histamine
Heparin
Tryptase–used to support clinical dx after pt is stable –marker for mast cell activation
Eosinophil chemotactic factors
What is the role of tumor necrosis factor-a?
Mediates septic shock Activated endothelium Causes WBC recruitment Vascular leak Causes cachexia in malignancy
Spontaneous pneumothorax seen in a tall, thin, young male is caused by what?
Rupture of apical sub pleural bleb or cysts
What 2 organisms show gamma hemolysis?
Enterococcus and Strep bovis
–No hemolysis
Enterococcus–seen after any type of GI/GU procedure
Strep bovis–colon cancer and Infectious endocarditis
What is the function of CN VII?
Facial movement Taste from anterior 2/3 of tongue Lacrimation Salivation Eyelid closing auditory volume modulation--stapedius
Anemia is characterized by ______ Hb concentration in the setting of normal SaO2, PaO2.
Decreased
What lung cancer has neuroendocrine origin?
Small cell (oat cell) carcinoma
Expresses chromogranin A and Neuron-specific enolase
What are the complications seen in pts with Lipoprotein lipase or apolipoprotien C-II deficiency?
Increased blood level of chylomicrons, TG, cholesterol
- -Pancreatitis
- -Hepatosplenomegaly
- -Eruptive/pruritic xanthomas
NO increased risk for atherosclerosis
HIV-associated dementia involves what?
Inflammatory activation of microglial cells –formation of microglial nodules around small areas of necrosis and may fuse to form multinucleated giant cells
–groups of activated macrophages/microglial cells
What is a common finding seen with Gallstone ileus–mechanical bowel obstruction caused when a large gallstone erodes into the intestinal lumen?
Pneumobilia–air in the biliary tract
