Approach to Headache/Meningitis/Encephalitis Flashcards
Primary headache disorders are ____ headache disorders
Benign
Secondary headache disorders are headaches that?
Are a sign of a pathologic disease
It is worrisome if the onset of a headache is after 50 yo, if accompanied with a fever, or if there are neurological symptoms?
YES - worrisome
When the brain is insulted, what are its 3 possible responses?
- Bleed
- Swell
- Seize
Any patient with a worrisome headache history or abnormal examination needs what 3 things?
- Imaging
- Lumbar puncture
- Arteriogram
Is it possible for CT scans to miss subarachnoid hemorrhages?
Yes - need a lumbar puncture to see it
What are the 5 Primary Headache Disorders?
- Common Migraine
- Classic Migraine
- Chronic Migraine
- Tension-type Headache
- Cluster Headache
A Common Migraine is lacking what that is present with a Classic Migraine?
Classic Migraine - has aura!
With Migraines, is the pain usually unilateral or bilateral and what types of behavior are common?
- Unilateral
- - Patient may retreat to dark and quiet room
Is there aura present with Common Migraines?
NO
- present with Classic Migraines
What is Aura and how long does it usually last?
- Lasts 15-30 mins
= Anything neurologic, usually visual symptoms, that precedes migraine
– Seen with Classic MIgraines
What defines a Chronic Migraine?
- Headache > 15 days per month
- Headache lasts > 4 hours
- Period of time > 3 months
With Migraines, do they usually prohibit normal daily activities?
YES
Do Tension-Type Headaches prohibit daily activities?
NO
Where is the common location of Tension-Type Headaches?
Bifrontal or Bioccipital
Migraines are sharp and throbbing pain. How are Tension-Type Headaches felt?
Dull, aching and squeezing pressure
Migraines and Headaches are usually experienced more commonly in females. In males, what is the most common type?
Cluster Headaches
What are Cluster Headaches associated with?
Obstructive Sleep Apnea
Describe the pain and location of Cluster Headaches
- 100% Unilateral
= Severe excruciating pain
What is unique behavior that is seen with Cluster Headaches?
Frenetic, pacing and rocking
There are many different treatments for Migraines. What class of drugs is commonly used and what is its MOA?
-Triptans = 5HT1 Agonists
What are a few contraindications to Triptan usage for Migraines?
- Ischemic heart disease
- Any vascular disease
- Uncontrolled HTN
What are a few classes of medications that can be used as PREVENTATIVE medicine for a Migraine?
- Antidepressants
- Beta blockers
- Calcium channel blockers
- Anticonvulsants
With CHRONIC Migraines, what is the best PREVENTATIVE treatment?
BOTOX injections for at least close to a year
What can BOTOX injections be used to prevent?
Chronic Migraines
What is Trigeminal Neuralgia?
Shooting electrical quality pain occurring in paroxysms in 1+ distributions of the Trigeminal Nerve
Shooting electrical quality pain occurring in paroxysms in 1+ distributions of the Trigeminal Nerve
Trigeminal Neuralgia
What is the treatment for Trigeminal Neuralgia?
Anticonvulsants = Carbamazepine or Oxcarbazepine
Inflammation of the meninges surrounding the brain or spinal cord
Meningitis
Inflammation of the brain tissue
Encephalitis
What is the overall most common cause of Meningitis?
Strep. Pneumoniae
If you are suspecting Bacterial Meningitis, what should be started before empirical antibiotics?
Dexamethasone (steroid)
With Bacterial Meningitis, why should Dexamethasone be started before starting antibiotics?
It prevents meningitis complications
Elevated opening pressure and extremely elevated WBCs in the CSF indicates what type of Meningitis?
Bacterial
Glucose levels for Bacterial, Viral, Fungal Meningitis in the CSF?
Bacterial = LOW Viral = Normal Fungal = LOW
What is Infectious Encephalitis?
Inflammatory process of the brain usually due to a virus
What is a common cause of Infectious Encephalitis?
Herpes Simplex Virus 1 (HSV1)
With Herpes Simplex 1 Encephalitis, what will the MRI and EEG demonstrate abnormalities in?
Temporal lobes
What is the treatment for Herpes Simplex 1 Encephalitis?
Acyclovir
A patient presents with Herpes Simplex 1 Encephalitis, they are treated and make a recovery. They later return with neuropsych symptoms. What has likely developed?
AUTOIMMUNE Encephalitis
What is Autoimmune Encephalitis?
Autoimmune cause of Encephalitis that can mimic infectious encephalitis
What symptoms are Autoimmune Encephalitis’s usually associated with?
Seizures/untreatable epilepsy
What are the 2 common types of Autoimmune Encephalitis?
- NMDA Encephalitis
2. LGI1 Encephalitis
If Autoimmune Encephalitis is suspected but the CSF results are NOT back yet, should you treat the patient?
YES
In what patients is NMDA Encephalitis more common?
Young/middle aged WOMEN
How does NMDA Encephalitis usually present?
SUDDEN psych symptoms!
With NMDA Encephalitis, what will the EEG show?
Extreme delta brush
What is NMDA Encephalitis commonly associated with the presence of?
Teratoma
What is the treatment for Autoimmune Encephalitis?
Immune suppression
How long does recovery take with NMDA Encephalitis?
May take a long time, upwards of a year
In what patients is LGI1 Encephalitis more common?
MEN
How does LGI1 Encephalitis usually present?
Faciobrachial dystonic seizures
– face and arm on the same side briefly seize
A patient presents with brief seizures involving one side of the face and the same sided arm. What associated abnormality may be seen on the brain and what behavior disturbance may be reported?
Abnormality of the brain = temporal lobe abnormality
Behavior disturbance = sleep disturbances
Do the faciobrachial seizures respond to drugs with LGI1 Encephalitis?
NO – often drug resistant
If the brain looks like grape jelly, what type of stroke occurred?
Hemorrhagic stroke
If the brain looks like rose’ wine, what type of stroke occurred?
Ischemic stroke that then underwent hemorrhagic conversion
With the treatment of a stroke, what symptom should NOT be treated?
Acute HTN should not be treated
With the treatment of a stroke, IV fluids should NOT contain what?
Glucose
If the NIH stroke scale number is lower, what does that correlate with?
LESS change of hemorrhage
With a stroke, what should be given within a few hours of the onset and what is a possible treatment if a large vessel is affected?
t-PA thrombolytic therapy
– Endovascular therapy (clot retrieval) along with t-PA for large vessels