AP02 Ventricles, CSF, and Meninges Flashcards
What are the layers of the Scalp?
skin dense connective tissue epicranial aponeurosis loose areolar connective tissue periosteum
What is the trabecular bit of the cranium called?
Dipole
What might arachnoid granulae form in the cranium?
granular fovoelae
What do emissary veins do?
pass from the outside of hte cranial cavity to the dural venous sinuses
Which artery lies deep to the pterion?
middle meningeal artery
What are the 2 key cell types of the blood brain barrier?
enodthelial cells
mural cells
What 2 categories of transporters do BBB endothelial cells express?
Efflux transporters
Influx transporters
What sort of molecules do BB endothelial cells have a very low amount of?
leukocyte adhesion molecules
limit the action of the immune system on the brain
Where are mural cells?
they line the BBB endothelium, although much of the cell body lies within the BM
How do mural cells attach to endothelial cells?
N-cadherin
What are mural cells derived from?
neural crest tissue
What is the endothelial : pericyte ratio in the brain compared to skeletal muscle?
brain - 1:1-3
muscle 100:1
What might cause leukocyte infiltration of the BBB?
disruption of the BM by matrix matalloproteinases
Where is the diaphragma sella?
superior to sella turcica and pituitary gland
inferior to the optic chiasm
How might masses extending into or from the pituitary fossa present?
snowman appearance caused by the constriction of the diaphragma
Where does the falx cerebri attach anteriorly?
crista galli of the ethmoid
Where does the falx cerebri attach posteirorly?
internal occipital protuberance