Anxiety Flashcards

1
Q

What is Fear?

A

An immediate alarm to present danger, characterized by a strong motivation to escape

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2
Q

What is Anxiety?

A

A mood state arising from the expectation of a future threat that is perceived as uncontrollable or unavoidable

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3
Q

Fear activates the ______ axis to bring about the fight-or-flight resposnse

A

SAM - Sympatho-Adreno-Medullary

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4
Q

What is characterized as a chronic mood state and cognitive process which is a response to a perceived future threat ?

A

Anxiety

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5
Q

what is characterized as a brief, automatic, emotional response to a imminent threat which results in intense autonomic arousal as a survival instinct ?

A

Fear

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6
Q

_______ is a normal and appropriate reaction to stressful situations

A

Anxiety

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7
Q

Anxiety _______ are when anxious feelings become so frequent or intense that they begin to take over an individuals life

A

Disorders

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8
Q

Individuals with anxiety disorders are at high risk of committing _____

A

Suicide

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9
Q

What are anxiety disorders most commonly comorbid with?

A

Depression

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10
Q

What is a panic attack?

A

An abrupt surge of intense fear or discomfort

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11
Q

What can most physical symptoms of panic attacks be attributed to?

A

Activation of the Sympathetic Nervous System

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12
Q

What is a panic disorder?

A

An anxiety attack in which panic attacks occur repeatedly without warning or a clear relation to external stimuli

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13
Q

What is it called when someone dreads the possibility of a future panic attack, which can lead to withdrawal from society and even cause more panic attacks?

A

Anticipatory Anxiety

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14
Q

What is a Phobia?

A

Anxiety disorder characterized by panic attacks directed at a specific object or situation

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15
Q

What is the most common anxiety disorder?

A

Phobia

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16
Q

What is social phobia?

A

Fear of being involved in society

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17
Q

What Agoraphobia?

A

Fear of being in public spaces

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18
Q

How doe most people attempt to control their phobias?

A

By avoiding triggering objects or situations

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19
Q

What area of the brain is responsible for emotional and motivated behaviours and becomes activated in times of fear?

A

Amygdala

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20
Q

What structure does the amygdala output to and what this structure regulate?

A
Hypothalamus 
Stress response (SAM and HPA)
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21
Q

The amygdala’s fast response to a stimulus occurs via the _________ and happens before we even know what it is we are afraid of

A

Thalamus

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22
Q

The amygdala’s slow response occurs as input from a fearful stimulus is relayed from the _______ to the _______ where it is processed, allowing you to identify the threat and response accordingly

A

Thalamus

Cortex

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23
Q

The _____ is our conscious control over anxiety and is involved in the final stages of reacting to danger by planning course of action required to address the situation

24
Q

Brain image studies on individuals with panic disorders reveal increased activation in the ___________ and ___________

A

Cingulate Cortex and Parahippocampal Gryus

25
What functions are the Cingulate Cortex and Parahippocampal Gyrus involved in?
Learning and Memory - particularly avoidance and fear learning
26
Brain image studies on individuals with panic disorders often show hypersensitivity in the ___________
Amygdala
27
What is hypersensitivity in the Amygdala tied with?
Enhanced response to anxiety-provoking stimuli
28
Brain image studies on individuals with panic disorders often reveal decreased activity in the ___________
PFC
29
What does loss of activity in the PFC during panic attacks explain?
Confusion Disorientation Aggressive Behaviour
30
Overall excessive excitatory _______ may enhance anxiety
Neurotransmission
31
What is exposure therapy?
An effective treatment for phobias which involves exposing patient to fear in small graduated increments in a safe and reassuring setting
32
What is the basis for Exposure Therapy?
Extinction
33
What is Extinction?
A process through which a stimulus that initially triggered a fear response gradually loses this effect as the trigger/reaction association is unlearned
34
Increased ________ through Exposure Therapy involves reduced reaction with repeated exposure to the trigger
Habituation
35
Increased _________ through Exposure Therapy involves increased belief in one's ability to manage their emotional responses
Self-Efficacy
36
Increased ______ _______ through exposure Therapy involves becoming more comfortable with experiencing fear and learning to attach belief's to the fear
Emotional Processing
37
What is characterized by persistently high levels of anxiety and worry occurring more days than not for at least 6 months
Generalized Anxiety Disorder (GAD)
38
What are common Psychological symptoms of GAD?
Feelings of fear, uneasiness, or worry Problems concentrating Rumination Irritable
39
What are common Physiological symptoms of GAD?
Restlessness Muscular Tension Fatigue Disturbed sleep
40
Expression of ______ receptors, which allow for sensing stress hormones, are altered in individuals with anxiety
Glucocorticoid
41
Individuals with GAD display reduced responsiveness to ____________ activation
Sympathetic Nervous System
42
Worry appears to increase _______ activation
Parasympathetic Nervous System
43
Individuals with GAD show increased activation of the _____ lobes in response to stressful stimuli and the _______ in anticipation of it
Frontal | Amygdala
44
GAD is an _____ based disorder which leads to increased ______ activity and reduced ______ activity
Anxiety PFC Sympathetic NS
45
Panic Disorder is a _____ based disorder which leads to decreased ______ activity and increased _______ and _______ activity (during panic attack)
Fear PFC Limbic Sympathetic NS
46
What is the most effective form of psychotherapy for treating Anxiety disorders?
Cognitive Behavioural Therapy (CBT)
47
What are drugs used to treat anxiety called?
Anxiolytics
48
Since excessive excitatory ______ is thought to enhance anxiety, most drugs to treat it increase ______ signalling
Neurotransmission | Inhibitory
49
What is the principal inhibitory NT in the brain?
GABA
50
What are two examples of Sedative Hypnotics?
Barbiturates | Alcohol
51
Which drug maximizes pore opening in the presence of GABA leading to hyperpolarization of the cell and suppression of neurotransmission?
Barbiturates
52
What are three examples of Benzodiazepines?
Xanax, Valium, Ativan
53
Which drug is a GABA receptor agonist which increases frequency of pore opening when GABA is present thereby increasing inhibitory signalling?
Benzodiazepines
54
What is an example of a SSRI?
Prozac
55
Which drug prevents serotonin reuptake leading to increased serotonin in the synapse?
SSRI