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PCOL FINALS > Antiviral Drugs > Flashcards

Antiviral Drugs Flashcards

1
Q

The organism that can cause harmful infections.

A

Infectious Agent

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2
Q

Five (5) Infectious Agent

A
  1. Protozoa
  2. Fungi
  3. Bacteria
  4. Virus
  5. Parasitic Worms
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3
Q

Single-Celled. Unicellular parasites of the animal kingdom.

Ex: Malaria, Amoeba

A

Protozoa

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4
Q

Unicellular structures of the plant kingdom.

Ex: Athlete’s Foot (Tinea Pedis)

A

Fungi

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5
Q

Unicellular structures that reproduce sexually or asexually, grow on cell-free media, and can exist in an inanimate environment.

Ex: TB, Leprosy

A

Bacteria

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6
Q

Obligate intracellular parasites that are among the smallest of the biologic agents known to infect human. They consist of encapsulated genetic material.

Ex: COVID-19

A

Virus

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7
Q

Also known as “Helminths”

Cestodes, Trematodes, Nematodes

A

Parasitic Worms

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8
Q

Smallest of all the self replicating organisms.

A

Viruses

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9
Q

They utilize host metabolic enzymes and host ribosome for protein.

A

Parasitic

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10
Q

Surrounded by Protein

A

Capsid

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11
Q

Sometimes an Outer Lipid

A

Envelope

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12
Q

Complete Viral Particle

A

Virion

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13
Q

A single stranded RNA virus. Viral nucleic acids, is helical or tubular. The enveloped virions. A club-shaped glycoprotein spikes in the envelope give the viruses, crownlike or coronal appearance.

A

COVID-19

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14
Q

Six (6) DNA Viruses

A
  1. Herpesvirus
  2. Papovavirus
  3. Adenovirus
  4. Hepadnavirus
  5. Poxvirus
  6. Parvovirus
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15
Q

It is also known as “Kissing Disease”; This is one of the most common viruses in humans. It causes infectious mononucleosis. It is associated with cancers.

A

Epstein-Barr Virus

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16
Q

Seven (7) RNA Viruses

A
  1. Picornaviridae
  2. Togaviridae
  3. Paramyxoviridae
  4. Flaviviridae
  5. Reoviridae
  6. Orthomyxoviridae
  7. Rhabdoviridae
17
Q

It can infect the person’s spinal cord, causing paralysis (can’t move parts of the body).

A

Polio Virus (Poliomyelitis)

18
Q

It is also known as “German Measles”

A

Rubella Virus

19
Q

It is also known as “Koplik’s Spot”

A

Measles Virus / Rubeola (Tigdas)

20
Q

It is also known as “Break Bone Fever”

A

Dengue Virus

21
Q

It is known for “Stomach Flu”; The most common cause of severe diarrhea in infants and children.

A

Rotavirus

22
Q

These are responsible for seasonal flu epidemics each year.

A

Influenza A and B

23
Q

A neurotropic virus that causes rabies in humans and animals.

A

Rhabdoviridae

24
Q

It weakens the person’s immune system by destroying important cells that fight disease and infection.

A

Retroviridae

25
Q

Two (2) Viral Enzymes

A
  1. DNA Polymerases
  2. RNA Polymerases
26
Q

Two (2) DNA Polymerases

A
  1. DNA-Dependent DNA Polymerase
  2. RNA-Dependent DNA Polymerase
27
Q

It is responsible for directing the synthesis of new DNA from deoxyribonucleotide triphosphates (dNTPs) opposite an existing DNA template, which contains the genetic information critical to an organism’s survival.

A

DNA-Dependent DNA Polymerase

28
Q

It is also known as “Reverse Transcriptase”; Initially isolated from retroviruses. A DNA polymerase enzyme that transcribes single-stranded RNA into DNA.

A

RNA-Dependent DNA Polymerase

29
Q

Two (2) RNA Polymerases

A
  1. RNA-Dependent RNA Polymerases
  2. DNA-Dependent RNA Polymerases
30
Q

An enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes synthesis of the RNA strand complementary to the given RNA template. RNA into RNA.

A

RNA-Dependent RNA Polymerases

31
Q

It catalyze the cleavage of specific peptide bonds in viral polyprotein precursors or in cellular proteins.

A

Viral Proteases

32
Q

A viral enzyme that catalyzes the integration of virally derived DNA into the host cell DNA in the nucleus.

A

Integrase

33
Q

It occurs both influenza A and B virus. Responsible for cleaving the receptor to allow virus release.

A

Neuraminidase

34
Q

It happens during viral replication. During the said process, viral genes undergo random “copying errors” (i.e., genetic mutations).

A

Viral Mutation

35
Q

It is also known as “Antigenic Drift”

A

Antigens

PCOL FINALS (9 decks)

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