Antituberculosos Flashcards

1
Q

Fármacos antituberculosos

A

Isoniazida
Rifampicina
Etambutol
Pirazinamida
Rifapentina

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2
Q

Isoniazida - MA

A

Inhibición de síntesis de ácido micólicos

Estos son componentes esenciales de la pared de micobacterias

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3
Q

Rifampicina - MA

A

Unión selectiva a RNA polimerasa micobacteriana dependiente de DNA

Inhibe la síntesis de RNA

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4
Q

Rifapentina - MA

A

Unión a RNA polimerasa micobacteriana dependiente de DNA

Inhibe la síntesis de RNA

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5
Q

Rifapentina - Contraindicaciones

A
  • Embarazo
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6
Q

Pirazinamida - MA

A

Probablemente sea la unión a ácido graso sintasa de M. Tuberculosis

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