antintidepressants and antipsychotics

Question 1

how do antidepressants work?

Answer 1

work by increasing certain neurotransmitter levels(chemical messengers between nerve cells) to improve communicaton between nerve cells in order to strengthen the circuits which regulate mood. there are different mechanisms and different neurotransmitters targeted(serotonin, norepenephrine, and dopamine.

Question 2

What are tricyclic antidepressants?

Answer 2

older class of antidepressants, work by blocking the reabsorption of serotonin and norepenephrine, also affect acetylcholine and histamine levels; responsible for certain side effects and why TCAs may be used for conditions other than depression.

Question 3

amitriptyline

Answer 3

Elavil, tricyclic antidepressant.

Question 4

Nortriptyline

Answer 4

Pamelor, tricyclic antidepressant.

Question 5

How do Tetracyclic Antidepressants(TeCAs)work?

Answer 5

older class of antidepressants; similar in structure to the tricyclic antidepressants, exact mechanism is unknown; increase serotonin and norepenephrine, affect other neurotransmitters with side effects.

Question 6

Mirtazapine

Answer 6

Remeron, tetracyclic antidepressant.

Question 7

How do Serotonin antagonist and reuptake inhibitors (SARIs) work?

Answer 7

Work by blocking the binding of serotonin at certain undesired receptors(serotonin antagonist) AND by blocking serotonin reabsorption(reuptake inhibitors); mechanism is not completely understood. older class of antidepressants with less selectivity, they affecct other neurotransmitters with side effects. often used for treatment of insomnia(off label use)

Question 8

Trazodone

Answer 8

Desyrel,Serotonin Antagonist and Reuptake inhibitor( SARIs)

Question 9

how do Selective Serotonin Reuptake inhibitors (SSRIs)

Answer 9

work by selectively blocking the reabsorption of serotonin; less side effects=most popular class. also used for a variety of anxiety related disorders.

Question 10

Sertraline

Answer 10

Zoloft, Selective serotonin Reuptake inhibitors(SSRIs)

Question 11

Fluoxetine

Answer 11

Prozac, Selective serotonin Reuptake inhibitors(SSRIs)

Question 12

Paroxetine

Answer 12

Paxil, Selective serotonin Reuptake inhibitors(SSRIs)

Question 13

Citalopram

Answer 13

Celexa, Selective serotonin Reuptake inhibitors(SSRIs)

Question 14

Escitalopram

Answer 14

Lexapro, Selective serotonin Reuptake inhibitors(SSRIs)

Question 15

how do Serotonin Norepinephrine Reuptake inhibitors. (SNRIs)

Answer 15

Work by selectively blocking the reabsorption of serotonin and norepenephrine. in addition to depression also used for anxiety disorders, nerve pain, and fibromyalgia.

Question 16

Venlafaxine

Answer 16

Effexor, Serotonin Norepenephrine Reuptake Inhibitors (SNRIs)

Question 17

Duloxetine

Answer 17

Cymbalta, Serotonin Norepinephrine Reuptake inhibitor. (SNRI)

Question 18

How do Norepenephrine Dopamine Reuptake inhibitors (NDRIs) work?

Answer 18

Work by selectively blocking the reabsorption of norepinephrine and dopamine. in additon to depression also used to help with smoking cessation.

Question 19

Bupropion

Answer 19

Wellbutrin, zyban, Norepinephrine dopamine Reuptake inhibitors(NDRIs)

Question 20

How do Antipsychotics work?

Answer 20

Used to treat schizophrenia, severe depression, severe anxiety, and symptoms of psychosis such as delusions, hallucinations, and paranoia. exact mechanism is unkown; work by blocking dopamine and serotonin receptors. Two categories: typical and atypical receptors. Typical(first generation): more likely to cause Extrapyramidal Symptoms(EPS) which are drug induced movement disorders affecting various parts of the body.

Question 21

Atypical Antipyschotics(Second Generation, SGAs)

Answer 21

Block dopamine receptors more selectively, which causes less eps side effects, cause more weight gain than typical antipsychotics, only atypical antipsychotics in the top 200 drugs are on this list.

Question 22

Risperidone

Answer 22

Risperidal, Atypical Antipyschotics(second generation, SGAs)

Question 23

Quetiapine

Answer 23

Seroquel, Atypical Antipyschotics(second generation, SGAs)

Question 24

Aripiprazole

Answer 24

Abilify, Atypical Antipyschotics(second generation, SGAs)