Antineoplastics

Question 1

Antineoplastics

C i s p l a t i n

Answer 1

• may cause tinnitus, blurry vision & fever
• electrolyte imbalances will occur

NCLEX Tips:
HYPO kalemia
HYPO calcemia
HYPO magnesemia
HYPO phospatemia

-Fluid needs to be ⇑⇑ 2-3 liters/day

Question 2

Antineoplastics

C y c l o p h o s p h a m i d e

Answer 2

• rinse mouth to prevent stomatitis
• may cause sterility
• Fluid needs to be ⇑⇑ 2-3 liters/day

Question 3

Antineoplastics

M e t h o t r e x a t e

Answer 3

-may cause thrombocytopenia

-may cause toxicity
ANTIDOTE: LEUCOVORIN

-Fluid needs to be ⇑⇑ 2-3 liters/day

Question 4

Antineoplastics

T a m o x i f e n

Answer 4

• affects women
• causes hot flashes, irregular periods, vaginal bleeding & discharge
• ⇑⇑ triglycerides & cholesterol

Question 5

Antineoplastics

In general:

Answer 5

1. Wt should be taken the day of med administration
2. avoid vaccinations during therapy
3. Med can cause an INCREASE in URIC ACID (HYPERURICEMIA)
4. Some Pxs will be given blood thinners with cancer meds to INCREASE EFFECTIVENESS.

Question 6

Antineoplastics

In general:

Answer 6

5. Use BLEEDING PRECAUTIONS
6. Special handling may be required (CYTOTOXIC)
   - may cause birth defects
   - NO PREGNANT /BREASTFEEDING Nurses to care for Px
   - Gowns, gloves, face protection if administering liquid
   - Gloves (1 pair) if administering solid
   - Gloves (2 pairs) if applying creams
7. Extravasation may occur at IV site
   1st priority: STOP infusion
   2nd priority: notify HCP