Antimicrobials 9 Flashcards

1
Q

Folate Antagonists

A

CELLMETABOLISMINHIBITORS

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2
Q

CELL WHAT ARE THE METABOLISM INHIBITORS

A

Sulfonamides
Pyrimidines
Sulfones

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3
Q

Sulfamethoxazole + trimethoprim

A

Co-trimoxazole

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4
Q

Sulfadiazine + trimethoprim

A

Co-trimazine

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5
Q

preferred for the prevention of infection of burn wounds

A

Silver sulfadiazine + mafenide

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6
Q

a prodrug of 5-Aminosalicylic acid (5-ASA) widely used in ulcerative colitis, enteritis, inflammatory bowel diseases, and rheumatic arthritis

A

Sulfasalazine

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7
Q

Sulfadoxine + pyrimethamine

A

Fansidar®: used in malaria

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8
Q

1st line therapy for acute toxoplasmosis

A

Sulfadiazine + pyrimethamine

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9
Q

bacterial dihydrofolate reductase inhibitor - Used for acute urinary tract infections

A

Trimethoprim

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10
Q

inhibit dihydropteroate synthetase

A

MOA of sulfones

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11
Q

used effectively in the long-term treatment of leprosy

A

Dapsone

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12
Q

C/l: patients with G6PD deficiency - may cause hemolytic anemia

A

Dapsone

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13
Q

inhibit dihydropteroate synthetase

A

MOA of Sulfonamides

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