Antilipemic Drugs Flashcards
2 primary forms of lipids in the blood
- TRIGLYCERIDE
- CHOLESTEROL
The combination of triglyceride or cholesterol with apolipoprotein
LIPOPROTEIN
Types of lipoproteins
- VERY LOW-DENSITY (VDL)
- LOW -DENSITY (LDL)
- HIGH -DENSITY (HDL)
A.k.A “Good cholesterol” ad is responsible for recycling of cholesterol
HDL
A.k.A “Bad cholesterol”
LDL
Normal amount of LDL cholesterol
<130 mg/dl
Normal amount of cholesterol
<200 mg/dl
Coronary Heart Disease is caused by (3):
- Elevated LDL
- Elevated triglycerides
- Decreased HDL
Desirable amount of HDL
> 60 mg/dl
Give the antilipemic drugs (6)
- HMG-CoA reductase inhibitors
- Bile acid sequestrants
- Niacin
- Fibric Acid alternatives
- Cholesterol absorption inhibitors
- Combination drugs
Drugs used to lower lipid levels
ANTILIPEMIC DRUGS
Increases cell absorption of LDL by blocking the enzyme HMG-CoA reductase
HMG-COA REDUCTASE INHIBITORS
It is used by the liver to produce cholesterol
HMG-COA REDUCTASE
Give HMG-CoA Reductase inhibitors
- ATORVASTATIN
- PRAVASTATIN
- SIMVASTATIN
The first line drug therapy for hypercholesterolemia
HMG-COA REDUCTASE INHIBITORS