Anticoagulants, Antiplatelets, Thrombolytics

Question 1

Prevents the formation of clots that inhibit circulation

Answer 1

ANTICOAGULANTS

Question 2

Prevent platelet aggregation

Answer 2

ANTIPLATELETS

Question 3

Attack and dissolve blood clots that have already formed

Answer 3

THROMBOLYTICS

Question 4

Alter the formation of platelet plug

Answer 4

ANTIPLATELET DRUGS

Question 5

Interfere the clotting cascade and thrombin formation

Answer 5

ANTICOAGULANT DRUGS

Question 6

Stimulate plasmin system to breakdown the formed clot

Answer 6

THROMBOLYTIC AGENTS

Question 7

This drug class exerts its action by decreasing the responsiveness of platelets to stimuli that cause it to clump or aggregate

Answer 7

ANTIPLATELET DRUGS

Question 8

Example of Antiplatelet

Answer 8

1. Aspirin
2. Clopidogrel
3. Ticlopidine
4. Tirofiban
5. Ticagrelor

Question 9

A drug that is effective and inexpensive treatment for suppressing platelet aggregation.

It inhibits cyclooxygenase (enzyme needed by the platelet to synthesize thromboxane)

Answer 9

ASPIRIN

Question 10

An enzyme needed by the platelet to synthesize thromboxane A2 (TxA2)

Answer 10

CYCLOOXYGENASE

Question 11

These drugs interfere with the normal clotting process by interfering with clotting cascade and thrombin formation

Answer 11

ANTICOAGULANTS

Question 12

Two oral agents of anticoagulants that directly inhibits thrombin

Answer 12

1. Dabigatran
2. Rivaroxaban

Question 13

These anticoagulants block formation of thrombin and prothrombin

Answer 13

1. Heparin
2. Antithrombin

Question 14

It most commonly prescribed to prevent Deep Vein Thrombosis (DVT) and acute pulmonary embolism after orthopedic or abdominal surgery

Used for prevention of blood clots in blood samples, dialysis,& venous tubing

Answer 14

HEPARIN

Question 15

Antidote for Heparin toxicity

Answer 15

PROTAMINE

Question 16

Directly inhibit thrombin from converting fibrinogen to fibrin

Answer 16

DIRECT THROMBIN INHIBITORS

Question 17

Examples of Direct Thrombin Inhibitors

Answer 17

1. Argatroban
2. Bivalirubin
3. Lepirudin

Question 18

It is mainly used to prevent thromboembolic conditions such as thrombophlebitis, pulmonary embolism, and embolism formation caused by atrial fib which can lead to stroke

Inhibit hepatic synthesis of vit. K, thus affecting clotting factors II, VII, IX, X

Answer 18

WARFARIN

Question 19

The anticoagulant of choice for lactating women because it does not enter breastmilk

Answer 19

HEPARIN

Question 20

A naturally occurring anticoagulant and is a natural safety feature in the clotting system

Answer 20

ANTITHROMBIN

Question 21

Treatment for warfarin overdose or uncontrollable bleeding

Answer 21

VITAMIN K (Phytonadione)

Question 22

These agents promote clot resolution: The process of activating the plasmin system to break down the thrombus or clot that has been formed

Answer 22

THROMBOLYTIC AGENTS

Question 23

This agents dissolves clot. It promotes plasminogen to plasmin.

Answer 23

THROMBOLYTICS

Question 24

Example of Thrombolytics

Answer 24

1. Streptokinase
2. Urokinase
3. Alteplase
4. Reteplase
5. Tenecteplase

Question 25

Indications of Thrombolytics (What it treats)

Answer 25

1. Myocardial infarction
2. Thrombolic stroke
3. Pulmonary embolism
4. DVT