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Pharmacology > Antihelminthics > Flashcards

Antihelminthics Flashcards

1
Q

Inhibits microtubule assembly; larvicidal and ovicidal

A

ALBENDAZOLE

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2
Q

DOC of Ascaris lumbricoides

A

ALBENDAZOLE

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3
Q

Inhibits microtubule synthesis and glucose uptake; Ovicidal

A

MEBENDAZOLE

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4
Q

DOC of Whipworm (Trichuris trichiura)

A

MEBENDAZOLE

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5
Q

DOC of Necator americanus

A

ALBENDAZOLE

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6
Q

DOC of Ancylostoma duodenale

A

ALBENDAZOLE

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7
Q

Inhibits microtubule synthesis and glucose uptake; inhibits fumarate reductase

A

Thiabendazole

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8
Q

DOC of Trichinosis (Trichinella spiralis)

A

THIABENDAZOLE

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9
Q

Immobilizes microfilariae

A

DEC (Diethylcarbamazine)

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10
Q

DOC of Filariasis

A

DEC (Diethylcarbamazine)

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11
Q

Intensifies GABA-mediated neurotransmission

A

Ivermectin

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12
Q

DOC of Strongyloides stercoralis

A

IVERMECTIN

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13
Q

Fever, headache, dizziness, rashes, pruritus, tachycardia, hypotension, pain in joints, muscles and lymph glands

Ivermectin, DEC

A

MAZOTTI REACTION

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14
Q

Stimulates nicotinic receptor at NMJ

A

PYRANTEL PAMOATE

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15
Q

DOC of Enterobius vermicularis

A

PYRANTEL PAMOATE

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16
Q

Increases membrane permeability to calcium causing paralysis

A

PRAZIQUANTEL

17
Q

DOC of Nematodes and Cestodes

A

PRAZIQUANTEL

18
Q

Nematodes

A 
Schistosoma
Paragonimus
Fasciola
Chlonorchis
Opistorchis
19
Q

Cestodes

A

Diphyllobutrium

20
Q

DOC of Echinococcus

A

ALBENDAZOLE

21
Q

Alternative drug for cestode infection

A

NICLOSAMIDE

22
Q

Uncoupled oxidative phosphorylation or by activating ATPase

Kills scolices and segments but has no effect on ova

A

NICLOSAMIDE

Pharmacology (16 decks)

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