3.3 Cardiovascular: Antiarrythmic Flashcards
Treatment of all types of arrythmias; WPW syndrome
SE: Drug-induced lupus
Procainamide
SE: cinchonism (headache, tinnitus, vertigo)
Quinidine
Post-MI arrhythmias; digitalis arrhythmias
SE: seizures
Lidocaine
Contraindicated post-MI, refractory arrhythmias
Propafenone; encainamide; moricizine; flecainide
Perioperative and thyrotoxic arrhythmias, SVT
Esmolol (IV)
SE: dose dependent torsades de pointes
Sotalol
Most efficacious anti arrhythmic
SE: skin deposits; pulmonary fibrosis; hyper/hypothyroidism
Amiodarone
Outpatient management of SVT
SE: Gingival hyperplasia
Verapamil
What are the effects of Class I anti arrhythmic on action potential duration?
Class IA: prolonged AP
Class IB: shortens AP
Class IC: no effect
Anti-arrhythmic Class IA
I Am the Queen who Proclaimed Diso’s pyramid
Quninidine, procainamide, disopyramide
Anti-arrhythmic Class IB
Best post MI
I Buy Mexican Tacos from Lily
Mexiletine; tocainide; lidocaine
Anti-arrhythmic Class IC
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Propafenone; flecainide; encainide
Amiodarone Toxicity
Pulmonary fibrosis; paresthesias; tremors; thyroid dysfunction; corneal deposits; skin deposits
Why are dihydropyridine calcium channel blockers not useful as anti-arrhythmic?
Evoke compensatory sympathetic discharge which facilitates arrhythmias rather than terminating them