2.1 Autonomics: Cholinergic Antagonists

Question 1

Induction of mydriasis and cyclopegia

Answer 1

Tropicamide, homatropine, cyclopentolate

Question 2

Sinus bradycardia

Answer 2

Atropine

Question 3

Parkinson’s disease

Answer 3

TRy to park your BENZ, BIP here.

trihexyphenidine, Benztropine, biperiden

Question 4

COPD

Answer 4

Ipratropium, thiotropium

Question 5

Motion sickness, sea sickness

Answer 5

Scopolamine

Question 6

Gastrointestinal spasm

Answer 6

Hyoscyamine

Question 7

Treatment for organophosphate poisoning

Answer 7

Atropine, pralidoxime

Question 8

S/S of Organophosphate poisoning

Answer 8

DUMBBELSS

Diarrhea, urination, miosis, bronchospasm, bradycardia, excitation, lacrimation, sweating, salivation

Question 9

Why is ipratropium the preferred bronchodilator in ots with comorbid COPD and heart disease

Answer 9

Less tachycardia

Less cardiac arrythmias

Question 10

Signs of atropine toxicity

Answer 10

HOT as a hare (fever)
DRY as a bone (anhidrosis)
RED as beet (flushing)
BLIND as bat (blurred vision)
MAD as a hatter (delirium, hallucination)