3 Cardiovascular: Anti-hypertensive Flashcards

1
Q

What is the formula for blood pressure?

A

Cardiac output X SVR

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2
Q

What is the expanded formula for blood pressure?

A

HR X SV X SVR

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3
Q

First line of drug for essential hypertension

A

JNC7 - HCTZ

JNC8- any but low dose

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4
Q

Hypertension with comirbid CHF/DM

SE: cough; angioedema
CI: bilateral RAS

A

Captopril

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5
Q

Used in ACE-inhibitor intolerance

A

Angiotensin receptor blocker (losartan)

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6
Q

Hypertension with comorbid BPH

A

Prazosin

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7
Q

Pre-eclampsia (maintenance medication)

SE: hemolytic anemia (positive coombs test)

A

Methyldopa

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8
Q

Pre-eclampsia (acute BP lowering)

SE: reflex tachycardia; drug-induced lupus

A

Hydralazine

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9
Q

Hypertensive emergency

SE: hypertrichosis

A

Minoxidil

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10
Q

Hypertensive emergency

SE: cyanide poisoning

A

Nitroprusside

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11
Q

Which part of the ETC is affected by cyanide?

A

Complex IV (cytochrome oxidase)

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12
Q

What is the antidote for cyanide poisoning?

A

Inhaled amyl nitrite
IV sodium nitrite
IV sodium thiosulfate

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