Antifungals Flashcards
Clotrimazole
Indications?
Dosage Forms?
Lotrimin
* LFTs may be monitored (with prolonged therapy of oral dosage form)
Fungal infections
Oral solid, topical, vaginal
Efinaconazole
Indications?
Dosage Forms?
Jublia
* Flammable med
Fungal infections
Topical
Fluconazole
Indications?
Dosage Forms?
Diflucan
* Interacts with many meds (atorvastatin, erythromycin, phenytoin, etc.)
* LFTs may be monitored (with prolonged therapy)
* NIOSH med
* Should be avoided in pregnant patients
Fungal infections
Injectable, oral powder (suspension), oral solid
Itraconazole
Indications?
Dosage Forms?
Sporanox
* Avoid use in heart failure patients
* Interacts with many meds (felodipine, methadone, ticagrelor, etc.)
* LFTs may be monitored (with prolonged therapy with oral form)
* Should be taken with a full meal
Fungal infections
Oral liquid, solid
Ketoconazole
Indications?
Dosage Forms?
Nizoral
* Oral form interacts with many meds (alprazolam, methadone, simvastatin, etc.)
* LFTs may be monitored (with prolonged therapy with oral form)
* Patients should avoid alcohol with oral dosage form
Fungal infections
Oral solid, topical
Miconazole
Indications?
Dosage Forms?
Monistat
* Avoid buccal dosage form in patients with a milk protein allergy
Fungal infections
Oral solid, topical, vaginal
Voriconazole
Indications?
Dosage Forms?
Vfend
* Interacts with many meds (alprazolam, simvastatin, etc.)
* LFTs will be monitored (with prolonged use)
* Oral solid form should be taken on an empty stomach
Fungal infections
Injectable, oral powder (suspension), oral solid
Amphotericin B
Indications?
Dosage Forms?
Ambisome
* High-alert med
* Interacts with aminoglycosides (gentamicin, tobramycin, etc)
* May cause allergic reactions
* SCr and BUN will be monitored
Fungal infections
Injectable
Nystatin
Indications?
Dosage Forms?
Mycostatin
* Oral suspension & topical forms should be used with caution in patients allergic to parabens
Fungal infections
Oral liquid, solid, topical
Terbinafine
Indications?
Dosage Forms?
Lamisil
* LFTS will be monitored (with oral dosage forms)
* Patients with liver disease should avoid oral solid form
Fungal infections
Oral solid, topical
Caspofungin
Indications?
Dosage Forms?
Cancidas
* Administer alone in IV line
* Interacts with many meds (carbamazepine, phenytoin, etc.)
Fungal infections
Injectable
Tavaborole
Indications?
Dosage Forms?
Kerydin
* Flammable med
Fungal infections
Topical
Ciclopirox
Indications?
Dosage Forms?
Loprox
* Lacquer topical form is flammable
Fungal infections
Topical
Clotrimazole/betamethasone
Indications?
Dosage Forms?
Lotrisone
* See special considerations for individual ingredients
Fungal infections
Topical
Nystatin/triamcinolone
Indications?
Dosage Forms?
Mycolog II
* See special considerations for individual ingredients
Fungal infections
Topical
