antidiarrheals Flashcards
Is a symptom of intestinal disorder
Diarrhea
Diarrhea
Frequent liquid stool
Patients with diarrhea should avoid
Milk products and foods rich in fat
Antidiarrheals should not used if
Fever is present
Also called acute diarrhea
Traveler’s diarrhea
Traveler’s diarhhea is usually caused by
E.coli
May be used to slow peristalsis and decrease the frquency of defecation
Loperamide (imodium)
Classifications of antidiarrheals:
- Opiates and opiate-related agents
- Somatostatin analogues
- Absorbents
- Miscellaneous
Decrease intestinal motility, thereby decreasing peristalsis.
Opiates
Is a common side effect of opium preparatione
Constipation
Duration of action of opiates
Approximately 2 hours
Frequently prescribed for traveler’s diarrhea
Diphenoxylate with atropine (Lomotil)
An active metabolite of diphenoxylate, but it is more potent than dihenoxylate
Difenoxin (motofen)
Prescribed to treat nonspecific and chronic diarrhea
Difenoxin (motofen)
It inhibts the secretion of many GIT hormones.
Somatostatin analogues
It reduces intestinal fluid secretion and pancreatic secretion
Somatostain analogues
Inhibit gallbladder contraction
Somatostatin analogues
Act by coating the wall of the GI tract and absorbing bacteria or toxins that cause diarrhea
Absorbents
Considered an absorbent because it absorbs bacterial toxins
Bismuth subsalicylate (Pepto-Bismol)
Are prescription drugs that have been used to treat diarrhea due to excess bile acids in the colon.
Colestipol and cholestyramine (questran)
Drug under miscellanous
Rifaximin
For treatment of traveler’s diarrhea caused by noninvasive strains of E.coli
Miscellaneous: Rifaximin
