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Pharmacology > Antibiotics_Marcrolides_March 19 > Flashcards

Antibiotics_Marcrolides_March 19 Flashcards

1
Q

What are the main types of macrolides?

A

-Arythromycin, azithromycin, clarithromycin, roxithromycin

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2
Q

What is the spectrum of Macrolides?

A

-Mostly G+ some G-

Strep, staph, H.Pylori, Syphillis, Tetanus

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3
Q

What is the mode of action of macrolides?

A

-Inhibit protein syntehsis

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4
Q

What is the main use of macrolides?

A

-Penicillin allergy

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5
Q

What is the main disadvantage of macrolides?

A

-Resistance develops over time

Higher risk of adverse effects

  • GI upset, dose dependant
  • Cholestatic hepatotoxicity
  • Cyp3A4 inhibitor

*Fewer noted in azithromycin, clarithromycin,

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Pharmacology (22 decks)

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