Antibiotics_Lincosamides_march 19 Flashcards
1
Q
What are the main types of Lincosamides?
A
Clindamycin (oral), lincomycin (IV)
2
Q
What is the biggest use of Lincosamides?
A
-Used if patient has true penicillin allergy
3
Q
What is the mode of action of lincosamides?
A
-Inhibit protein synthesis
4
Q
What is the spectrum of lincosamides?
A
-G+ and anaerobes affected
5
Q
What are the main risks associated with lincosamides?
A
-Greater risk of adverse effects and allergy
(in particular diarrhoea 2-20%; allergic rash 10%)
-Diarrhoea can be sever to the point of fatal and worsens with dosage
