Antibiotics broken down info Flashcards
peniciilin
cell wall
cephalosporins
cell wall
bacitracin
cell wall
vancomycin
cell wall
aminoglycoside
DNA/protein synthesis
tetracyclines
DNA/protein synthesis
chloramphenicol
DNA/protein synthesis
macrolides
DNA/protein synthesis
polymyxin B
plasma membrane
rifamycin
ribosome/nucleic acids
quinolones
ribosome/nucleic acids
sulfonamides
metabolic pathways
isoniazid
metabolic pathway
how many are related to penicillin
50 related
what are cephalosporins
target gram -
injected
expensive
resistant to penicillinase
what are bacitracin
gram +
topical
stop linear peptidoglycan strand synthesis
what are vancomycin
affect penicillinase producers
stops cell wall synthesis
used to be last line
what are aminoglycosides
gram -
changes the 30s subunit shape
damage to auditory nerve and kidneys
what are tetracyclines
stop tRNA attachment
animal feed
discolor teeth in children
liver damage if pregnant
what are chloamphenicol
inhibit peptide bond formation
toxic
aplastic anemia
what are macrolides
stoops mRNA through ribosomes
gram +
oral-children
what are polymyxin B
bacteriocidal
toxic-kidneys and nervous cells
gram +
humans-similar plasma membrane
what are rifamycin
inhibit mRNA synthesis
red urine, sweat, saliva, tears
penetrate tissue
what are quinolones
bacteriocidal
inhibit DNA replication
fluoroquinolones develop
what are sulfonamides
synthetic inhibit enzyme and production of folic acid
bacteriostatic
broad spectrum
allergic reactions
what are isoniazid
treat TB
affect enzyme for mycolic acid synthesis
