Antibiotics broken down info Flashcards

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1
Q

peniciilin

A

cell wall

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2
Q

cephalosporins

A

cell wall

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3
Q

bacitracin

A

cell wall

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4
Q

vancomycin

A

cell wall

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5
Q

aminoglycoside

A

DNA/protein synthesis

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6
Q

tetracyclines

A

DNA/protein synthesis

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7
Q

chloramphenicol

A

DNA/protein synthesis

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8
Q

macrolides

A

DNA/protein synthesis

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9
Q

polymyxin B

A

plasma membrane

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10
Q

rifamycin

A

ribosome/nucleic acids

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11
Q

quinolones

A

ribosome/nucleic acids

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12
Q

sulfonamides

A

metabolic pathways

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13
Q

isoniazid

A

metabolic pathway

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14
Q

how many are related to penicillin

A

50 related

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15
Q

what are cephalosporins

A

target gram -
injected
expensive
resistant to penicillinase

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16
Q

what are bacitracin

A

gram +
topical
stop linear peptidoglycan strand synthesis

17
Q

what are vancomycin

A

affect penicillinase producers
stops cell wall synthesis
used to be last line

18
Q

what are aminoglycosides

A

gram -
changes the 30s subunit shape
damage to auditory nerve and kidneys

19
Q

what are tetracyclines

A

stop tRNA attachment
animal feed
discolor teeth in children
liver damage if pregnant

20
Q

what are chloamphenicol

A

inhibit peptide bond formation
toxic
aplastic anemia

21
Q

what are macrolides

A

stoops mRNA through ribosomes
gram +
oral-children

22
Q

what are polymyxin B

A

bacteriocidal
toxic-kidneys and nervous cells
gram +
humans-similar plasma membrane

23
Q

what are rifamycin

A

inhibit mRNA synthesis
red urine, sweat, saliva, tears
penetrate tissue

24
Q

what are quinolones

A

bacteriocidal
inhibit DNA replication
fluoroquinolones develop

25
Q

what are sulfonamides

A

synthetic inhibit enzyme and production of folic acid
bacteriostatic
broad spectrum
allergic reactions

26
Q

what are isoniazid

A

treat TB
affect enzyme for mycolic acid synthesis