Antibiotics Flashcards
Adverse side effects of Quinolones
headache, dizziness, insomnia,depression, nausea, vomiting ,diarrhea, constipation, ruptured
tendon
Aminoglycosides administration
parentally (poor absorption through GI tract)
Antibiotic effective against MRSA
Vancomycin
Antibiotic effective against VRE
Daptomycin
These are examples of Quinolones
Ciprofloxacin (Cipro),
Norfloxacin (Noroxin),
Levofloxacin (Levaquin)
Therapeutic drug monitoring
Dosages are adjusted to maintain known optimal
levels that maximize drug efficacy and minimize the
risk for toxicity
Drugs (minerals) that interact with Quinolones
antacids, calcium, magnesium,
iron, zinc, dairy
Most important means of preventing the spread of
infection
handwashing
These labs are frequently monitored to assess renal function in a person
BUN and Creatinine
Antibacterial/Antiprotozoal used to treat intra abdominal
and gynecologic infections
Metronidazole (Flagyl)
MRSA
methicillin-resistant staphylococcus aureus
Multigenerational antibiotic.
Use: UTI. Precautions: broadspectrum, contraindicated in
renal dysfunction, urine will have brown discoloration.
Nitrofurantoin
Macrodantin
Have excellent oral absorption
and are bactericidal broad spectrum antibiotics
Quinolones
Quinolone used
to treat Anthrax
Ciprofloxacin
Toxic side effects of aminoglycosides
nephrotoxicity and ototoxicity
Used to treat systemic infections
Aminoglycosides
Vancomycin
Vancocin
Treatment of choice for MRSA and other gram-positive infections. Oral vancomycin is indicated for the
treatment of antibiotic-induced colitis (C.
difficile) and for the treatment of
staphylococcal enterocolitis.
Must monitor blood levels to ensure
therapeutic levels and prevent toxicity
May cause ototoxicity and nephrotoxicity
VRE
vancomycin resistant enterococcus
methicillin-resistant staphylococcus aureus
MRSA
Potent antibiotics with serious toxicities. Used for gram-negative and some gram-positive bacteria.
Aminoglycosides
Therapeutic drug monitoring
Dosages are adjusted to maintain known optimal levels that maximize drug efficacy and minimize the risk for toxicity.
nephrotoxicity and ototoxicity
Toxic side effects of aminoglycosides
parentally (poor absorption through GI tract)
Aminoglycosides administration
These labs are frequently monitored to assess renal function in a person taking aminoglycosides
BUN and Creatinine
Have excellent oral absorption and are bactericidal broad-spectrum antibiotics
Quinolones
Ciprofloxacin (Cipro), Norfloxacin (Noroxin), Levofloxacin (Levaquin)
Ciprofloxacin
antacids, calcium, magnesium, iron, zinc, dairy
Drug that interact with Quinolones
headache, dizziness, insomnia, depression, nausea, vomiting , diarrhea, constipation, ruptured tendon
Adverse side effects of Quinolones
often used for bone infections
Clindamycin (Cleocin)
Antibacterial/Antiprotozoal used to treat intra abdominal and gynecologic infections
Metronidazole (Flagyl)
Multigenerational antibiotic. Use: UTI. Precautions: broad-spectrum, contraindicated in renal dysfunction, urine will have brown discoloration.
Nitrofurantoin (Macrodantin)
