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Farma > Antibióticos inhibidores de sintesis proteíca > Flashcards

Antibióticos inhibidores de sintesis proteíca Flashcards

1
Q

Inhibidores de 30 s

A

Aminoglucosidos
Tetraciclinas

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2
Q

Aminoglucosidos

A

Gentamicina
Neomicina
Estreptomicina

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3
Q

MA de aminoglucosidos

A

Bactericida
Usa cargas +

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4
Q

Indicaciones generales de aminoglucosidos

A

Solo usar cuando no hay alternativa
Endocarditis/ neumonía/ tuberculosis
Y. pestis
P. aeruginosa

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5
Q

Tetraciclinas

A

Doxiciclina
Tetraciclina
Tifeciclina

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6
Q

MA de tetraciclinas

A

Bacteriostatico
Bloquea union ARNm y ARNt

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7
Q

Indicaciones generales de tetraciclinas

A

Lyme
Fiebre Q

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8
Q

Contraindicaciones de tetraciclinas

A

Comida disminuye absorción
Antiacidos y hierro impiden absorción

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9
Q

EA de tetraciclinas

A

Coloracion e hiperplasia esmalte
Nefrotoxico
Hepatotoxico

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10
Q

Inhibidores de 50s

A

Macrolidos
Clindamicina
Cloranfenicol

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11
Q

Macrolidos

A

Eritromicina
Azitromicina
Cloritromicina

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12
Q

MA de macrolidos

A

Bacteriostatico/ bactericida
Bloqueo peptidil tranferasa

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13
Q

Indicaciones generales de Macrolidos

A

Infecciones respiratorias
Enf, ulcerosa peptica
Tx enfermedades peptica

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14
Q

Espectro de macrolidos

A

S. pyogenes, neumoníae
M. pneumoniae
H. pylori

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15
Q

EA de macrolidos

A

Inhibidores potentes
Estomatitis
pirosis
Graves: hepatitis y prolongation de qt

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16
Q

MA de clindamicina

A

Inhibe traslocación base

17
Q

Indicaciones generales de clindamicina

A

Gangrena gaseosa
Fascitis necrosante
Inf pulmonares y pleurales

18
Q

Espectro de clindamicina

A

SARM
C. perfringens

19
Q

EA de clindamicina

A

Diarrea: 50% c. difficile
megacolon toxico

20
Q

MA de cloranfenicol

A

Bacteriostatico/ Bactericida
Bloqueo de peptidil transferasa

21
Q

Indicaciones generales de cloranfenicol

A

2da elección meningitis
Abcesos cerebrales

22
Q

Espectro de cloranfenicol

A

h. influenza
s. pneumoniae
N. meningitides

23
Q

Farmaco usado cuando hay alergias a B lactamicos

A

Claranfenicol

24
Q

EA de cloranfenicol

A

Anemia aplasica mortal (Sx niño gris)

25
Q

MA de quinospristina y linezolid

A

Inhibidor de 50 s

26
Q

Indicaciones generales de quinopristina y linezolid

A

Bacterias multiresistentes

27
Q

Espectro de quinopristina y linezolid

A

Gram +: VRE SARm
Gram -

28
Q

EA de quinopristina y linezolid

A

trombocitopenia
hiperbilirrubinemia

Farma (11 decks)

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