AINES Flashcards by maria lopez garcia

Q

AINES con afinidad a COX 1

A

Ketorolaco
Naproxeno
Indometacina
Ibuprofeno

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Q

AINEs con afinidad a COX 2

A

Piroxicam
Diclofenaco
Celecoxib
Meloxicam

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Q

Funciones de COX1

A

Todas las celulas
Funcion gastrica
Vasodilatación renal
Agregacion plaquetaria

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Q

Funciones de la COX 2

A

Inflamación
Edema
Citocinas
Fiebre

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Q

EA de Aspirina

A

Asociado a Sx de Reye
Tinutus

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Q

EA de Ketorolaco

A

Mayor posibilidad de EA renales
Ulcera gastrica

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Q

EA de naproxen

A

Menor riesgo cardiovascular

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Q

Celecoxib

A

Mayor riesgo de EA

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Q

AINE con mayor eficacia

A

Ketorolaco

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Q

Funcion de aspirina en dosis bajas

A

Cardioprotector

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Q

No es util en el dolor agudo

A

Celecoxib

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Q

Indicaciones de Diclofenaco

A

Acumulación en articulaciones e inflamación

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Q

MA de Paracetamol

A

Inhibidor de COX en SNC

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Q

Indicaciones generales de paracetamol

A

Dolor leve a moderado
No antiinflamatorio

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Q

EA de paracetamol

A

Puede producir hepatotoxicidad

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Q

MA de gabapentina y pregabalina

A

Antagonista Ca+
Se une a subunidad alfa

Q

Indicaciones generales de gabapentin y pregabalin

A

Dolor neuropatico
Convulsiones parciales

Q

ADME de pregabalin

A

Absorción lineal

Q

EA de gabapentin y pregabalin

A

Edema
Ataxia
Somnoliencia
Categoria C