Antibacterial Agents Flashcards
what are the 2 different types of antibiotic activity?
bactericidal
bacteriostatic
bactericidal inhibits the growth of the bacteria
true or false?
false, bacteriostatic
Drugs that are effective on a limited number of microorganism types are?
drugs that are effective on
many microorganism types are?
1- narrow-spectrum antibacterial drugs
2- broad-spectrum antibacterial
drugs.
the drug concentration that inhibits 90% of these strains in experiments on many
susceptible strains of a bacterium or microorganism species is?
MIC90
the minimum drug concentration that kills more than 99.9% of
bacteria under standard conditions in culture medium is?
minimum bactericidal
concentration (MBC).
If a bacteria develops resistance to a certain antibacterial agent and that resistance can
decrease sensitivity to some other chemotherapeutic drugs (especially chemically near
groups). This is called?
cross resistance.
what are the three approaches to chemoprophylaxis?
1- protect healthy people
2- prevent the development of secondary bacterial infection in people with
another disease
3- related to surgical interventions
what is the mechanism of action for Penicillin, Cephalosporin ?
Disrupts cell wall synthesis
aminopenicillin is used for influenza
true or false?
true
Less resistance than seen with penicillin because they have a more stable β-lactam ring.
this bactericidal is?
Cephalosporin
(Aminoglycosides,
Macrolides, Chloramphenicol, Tetracyclines)
inhibits what?
bacterial protein synthesis
what is the protype of Macrolides?
Erythromycin
which antibacterial agent can be used for lower respiratory tract ?
Macrolides
what is Used for treatment of skin and skin structure infections caused by S. aureu?
Tetracyclines
Sulfonamide and trimethoprim=Antibacterial
synergism
together are ?
Bacteriostatic antibacterial agents for inhibiting DNA synthesis
