anti-platelet/anticoagulation drugs (test 2) Flashcards
Heparin
unfractionated heparin
binds to antithrombin III –> bind Xa and IIa
LMWH
low molecular weight heparin (smaller than heparin)
binds to antithrombin III –> bind Xa
fondaparinux
binds to antithrombin III –> bind Xa
higher affinity to antithrombin III compared to LMWH
bivalirudin
direct thrombin inhibitor
used to reverse HIT
argatorban
direct thrombin inhibitor
used to reverse HIT
dabigatran
direct thrombin inhibitor
used to reverse HIT
rivaroxaban
direct Xa inhibitor
apixaban
direct Xa inhibitor
warfarin
vitamin K epoxide reductase (VKOR) inhibitor
clopidogrel
antiplatelet agent
ADP (P2-Y12) receptor antagonist
ticgrelor
antiplatelet agent
ADP (P2-Y12) receptor antagonist
prasugrel
antiplatelet agent
ADP (P2-Y12) receptor antagonist
aspirin
antiplatelet agent
irreversibly acetylates COX-1 and COX-2 (for the life of the platelet)
abciximab
GPIIb/IIIa receptor antagonist
monoclonal antibody
tirofiban
GPIIb/IIIa receptor antagonist