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FINAL FARMACOLOGIA > Anti gram + > Flashcards

Anti gram + Flashcards

1
Q

Tos por mas de 15 dias ordenar…..

A

Baciloscopio

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2
Q

Primera linea de TBC

A
  • Rifampicina
  • Isoniazida
  • Pirazinamida
  • Etambutol
  • Estreptomicina (mas nefrotoxico)
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3
Q

Segunda linea en TBC

A
  • Etionamida
  • Triacetazona
  • PAS
  • Cicloserina
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4
Q

Medicamento pilar en TBC

A

Isoniazida

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5
Q

Mecanismo de acción de Isoniazida

A

Inhibe sintesis de ADN y Acido Micolico

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6
Q

Mecanismo de acción de Rifampicina

A

Inhibe sintesis de ADN siendo bactericida en crecimiento; Intra y extra celular

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7
Q

Mecanismo de acción de glicopeptidos

A

Se une a la D-Alanina terminal inhiendo sintesis de pared celular; 2da fase

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8
Q

Espectro de acción de glicopeptidos

A

Anaerobios y Gram +

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9
Q

Diferencia entre Vacomicina y Teicoplanina

A
  • Costo

- Teicoplanina mas cara por menos toxicidad

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10
Q

Espectro de acción de Vancomicina

A
  • Enterococcus Faecalis
  • S.Aureus (SAMR)
  • C. Difficille
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11
Q

RAMs de Vancomicina

A
  • Sx hombre rojo; aumentar cadda 3 horas
  • Flebitis
  • Nefro y ototoxicidad
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12
Q

Espectro de Linezolid

A
  • Inefectivo en Gram -

- Infecciones en Gram +; S.Aureus vancomicino resistente y Enterococcus Faecium

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13
Q

Mecanismo de acción de Estreptograninas

A

Inhibe sintesis de proteinas ; subunidad 50S

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14
Q

Vida media de estreptograninas

A

Menos de 1 hora

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15
Q

Espectro de Estreptograninas

A
  • Diplococcus Gram -
  • S.Aureus y Pyogenes
  • Enterococcus Faecium resistente
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16
Q

Mecanismos de acción de Daptomicina

A
  • Menos potencial de membrana bacteriana

- Inhibición de sintesis de ADN, ARN y proteinas

17
Q

Espectro de Daptomicina

A

-Cocos Gram +

18
Q

Paraclinicos en Daptomicina

A

-CPKs

19
Q

Condiciones especiales para Daptomicina

A
  • Insuficiencia renal cronica

- Osteomielitis

20
Q

Mecanismo de acción de Macrolidos

A

-Inhiben sintesis proteica subs 50s

FINAL FARMACOLOGIA (9 decks)

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