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Boards Review > Anti-fungals > Flashcards

Anti-fungals Flashcards

1
Q

Amp B

A

binds ergosterol -> holes in membrane

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2
Q

Nystatin

A

binds ergosterol -> holes in membrane

topical

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3
Q

Flucytosine

A

inhibits DNA and RNA biosynthesis

systemic infections

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4
Q

Azoles

A

inhibit ergosterol synthesis- bind CYP450

testosterone inhibition, liver dysfxn

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5
Q

Terbinafine

A

Inhibits squalene epoxidase

Dermatophytes

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6
Q

Echinocandins

A

inhibit cell wall synthesis (B-glucan)

invasive aspergillosis, candida

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7
Q

Griseofulvin

A

interferes w/ microtubule dysfxn- disrupt mitosis
superficial infections
teratogen, carcinogen

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Boards Review (12 decks)

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