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MRCP Pharmacology > Anti-arrhythmics > Flashcards

Anti-arrhythmics Flashcards

1
Q

Mechanism of action of Class 1 anti-arrhythmics

A

ALL Block sodium channels

1a: Increases duration of cardiac myocyte action potential (AP)

1b: decreases AP duration

1c: No effect on AP duration

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2
Q

Examples of class 1a anti-arrhythmics

A

Quinidine
Procainamide
Disopyramide

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3
Q

Examples of Class 1b anti-arrhythmics

A

Lidocaine
Mexiletine
Tocainide

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4
Q

Describe the mechanism of action of Class II anti-arrhythmics

A

beta-adrenoceptor antagonists

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5
Q

Give examples of Class II anti-arrhythmics

A

Propranolol
Atenolol
Bisoprolol
Metoprolol

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6
Q

Mechanism of action of class III antiarrhythmics

A

block potassium channels

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7
Q

Examples of Class III antiarrhythmics

A

Amiodarone
Sotalol
Ibutilide
Bretylium

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8
Q

Mechanism of Class IV antiarrhythmics

A

Calcium channel blockers

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9
Q

Examples of Class IV antiarrhythmics

A

Verapamil
Diltiazem

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MRCP Pharmacology (22 decks)

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