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Pharmacology > Anti-angina & HF drugs > Flashcards

Anti-angina & HF drugs Flashcards

1
Q

Ultrashort-acting nitrate used in cyanide poisoning

A

Amyl nitrate

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2
Q

Antidote for cyanide poisoning

A

Inhaled amyl nitrate + IV sodium nitrate + IV sodium thiosulfate

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3
Q

Short-acting nitrate used for angina and ACS; available in transdermal patches; causes dangerous hypotension w/ PDE inhibitors (Viagra)

A

Nitroglycerin

ISMN: maintenance; ISDN: acute

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4
Q

Dihydropiridine CCBs

A 
(-Dipines)
Nifedipine
Amlodipine
Felodipine
Nicardipine
Nisoldipine
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5
Q

Non-dihydropiridine CCBs

A

Verapamil (used in Migraine)

Diltiazem (used in Raynaud’s phenomenon)

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6
Q

Drugs causing gingival hyperplasia

NapaCa-Pangit ng gingiVa mo!

A

Nifedipine
Cyclosporine
Phenytoin
Verapamil

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7
Q

Angina prophylaxis; masks hypoglycemia in DM patients; cause erectile dysfx

A

Betablockers

Propanolo, atenolol, metoprolol

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8
Q

Type of heart failure that presents with orthopnea, PND, and pulmo congestion

A

Left-sided HF

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9
Q

Type of heart failure that presents with hepatomegaly, edema, engorged neck veins

A

Right-sided HF

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10
Q

Cardiac glycoside inhibiting Na/K ATPase; also used in nodal arrhythmias; Causes yellow visual changes

A

Digoxin

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11
Q

Drugs with narrow therapeutic index

WALA na Cyang PaPa! VasTeD na!

A 
Warfarin
Aminoglycosides
Lithium
Amphotericin B
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Theophylline
Digoxin
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12
Q

Digitalis toxicity is increased by _____K, _____ Mg and ____Ca

A

hypoK
hypoMg
hyperCa

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13
Q

Tx for Digitalis toxicity

A 
Correction of K/Mg deficiency
Antiarrhythmic drugs (DOC: lidocaine)
Digoxin Ab (Digifab, Digibind)
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14
Q

1st line therapy for both sys and diastolic failure

A

Diuretics

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15
Q

Diuretic of choice for acute heart failure

A

Furosemide

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16
Q

Diuretics of choice for chronic heart failure

A

Spirinolactone

Eplerenone

17
Q

First line drugs for chronic heart failure

A

Angiotensin Antagonists

18
Q

B1-selective antagonist useful in acute heart failure; not appropriate for chronic failure

A

Dobutamine

Dopamine

19
Q

Betablockers used to reduce progression of chronic HF; detrimental if systolic dysfx is marked

A

Carvedilol, labetalol, metoprolol

20
Q

PDE inhibitors resulting in inc cAMP

A

inamrinone

milrinone

21
Q

Vasodilators used in in acute severe failure with congestion

A

Nitroprusside

Nitroglycerin

22
Q

Reduce mortality due to HF in African Americans

A

Hydralazine

Isosorbide dinitrate

23
Q

Drugs shown to improve survival in heart failure

A

ACEI
Betablockers
Aldosterone antagonists

24
Q

Characteristic ECG tracing that shows QT interval prolongation

A

Torsades de pointes

25
Q

DOC for prinzmetal angina/ vasospastic angina

A

CCB

Pharmacology (10 decks)

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