Anatomy - Mammary Gland and Thoracic Wall Flashcards
Definition of the thorax?
Area between neck and abdomen
What are the mammary glands part of?
Superficial fascia
What do breasts primarily consist of?
Fat
Where is the breast located?
- Deep to dermis- Superficial to deep fascia superficial to the pectoralis major and serratus anterior- Inferior to clavicular edge- Superior to rectus sheath- Lateral to the edge of the latissisimus dorsi - Medial to the sternum
What gives shape to the breasts? Describe their location
The suspensory ligaments of Cooper Extend perpendicularly from the deep fascia superficial to the pectoralis major to the skin
Does the amount of milk produced by breasts vary with their size? Why/Why not?
NOPE because the amount of glandular tissue does not vary with size
Describe the pathway of milk in the breast.
Breast lobules produce milk => lactiferous ducts => lactiferous sinus => 12-15 ductal openings into the nipple
Are lactiferous ducts found in all women?
NOPE, they disappear after menopause because they depend on hormones
Do both male and females have an axillary breast tail?
YUP
What does the external surface of the breasts consist of?
- Pigmented nipple2. Areolar tissue with glands
Role of areolar glands?
Sebaceous glands that enlarge during pregnancy to help lubricate the skin for breast feeding
When do the nipple and areola become more pigmented? How come? In which population is this exacerbated?
During the last trimester of the 1st pregnancyDue to increased amount of melaninIn African Americans
Where is the ONLY muscle of the mammary gland located? What kind? When does it contract?
The areola - smooth muscleContracts upon stimulation
What are the 5 arteries providing blood supply to the breasts?
- Internal thoracic artery branches (to intercostals)2. Lateral thoracic artery branches3. Thoracodorsal artery 4. Intercostal artery (perforators)5. Thoracoacromial artery
What is another name for the internal thoracic artery in females?
Internal mammary artery
Is the breast affected by coronary bypass surgery in females in which the internal thoracic artery is harvested? Why/Why not?
NOPE, because of the extensive and redundant blood supply of the breast
What are the 2 tissue types of the breast?
- Glandular tissue2. Supportive tissue
What are the 3 types of supportive tissue of the breast?
- Suspensory ligaments2. Fat 3. Connective tissue
Describe the venous drainage of breasts.
Follows the same tracts as the arteries
What are the 4 types of lymph nodes that drain the breast? Which one is responsible for the majority of the lymphatic drainage?
- Axillary lymph nodes*** (75% of drainage)2. Supraclavicular lymph nodes3. Internal mammary lymph nodes 4. Abdominal lymph nodes (25% of drainage)
What is another name for internal mammary lymph nodes?
Parasternal lymph nodes
Which breast lymph nodes are at greater risk for cancer metastases?
Supraclavicular lymph nodes
How can breast cancer move from one breast to the other?
Via internal mammary lymph nodes through the pectoral major fascia
What artery does the lateral thoracic artery branch from?
Axillary artery
What artery does the internal thoracic artery branch from?
Subclavian artery
Why can cancer spread easily from the breasts to the vertebral column/brain?
Because there are no valves between the intercostal veins and the vertebral veins
How do surgeons divide breasts?
4 quadrants
Where do most breast cancers occur? In what lymph nodes do these drain?
Superior lateral quadrantsDrain into axillary lymph nodes
Can surgery alone potentially cure breast cancer?
If caught early enough, yes
What are 5 explanations for felt breast lumps? List in order of %
- Fibrocystic changes2. No disease3. Miscellaneous benign4. Cancer5. Fibroadenoma
Incidence of lifetime breast cancer in women?
1:7 by age 90
Is breast cancer the most common visceral cancer in women?
YUP
Does breast cancer risk increase with age?
YUP
What are the 7 breast cancer screening techniques? Which one is the gold standard for significantly impacting survival rates?
- Self examination2. Physician performed examination3. Mammogram***4. Ultrasound5. Ductography6. MRI7. Needle biopsy
When does breast examination indicate breast cancer? Explain each symptom.
- Skin dimpling because the cancer cells are attacking the suspensory ligaments of Cooper and shortening them 2. Prominent vascular patterns because a fast-growing tumor will have a large vascular demand and will cause dilation of superficial veins 3. Skin edema due to lymph accumulation in the skin (orange peel appearance) because the cancer is attacking the subcutaneous lymphatics 4. Nipple retraction due to shortening of lactiferous ducts
Does breast self-examination increase breast cancer survival rates?
Unsure
What are the 2 views that mammograms are conducted in?
- Craniocaudal view2. Medial-lateral oblique view
What are breasts ultrasounds used for?
To distinguish fluid-filled cysts (light) from solid masses (dark)
What are breasts MRI used for?
To evaluate how extensive the breast cancer is
How is breast examination conducted?
- Breast is palpated systematically either in concentric circles or by quadrant 2. Flat parts of the fingers are used to press down to reveal masses3. Nipple is squeezed to detect bleeding or discharge
What are breast fibrocystic changes due to?
Usually due to menstrual cycle
What is fibroadenoma?
Benign neoplasm of glandular epithelium with significant increase in connective tissue
What color would a breast tumor appear as on a mammogram?
White
What is the purpose of a needle biopsy to detect breast cancer?
Usually done after a mammogram has identified a tumor - done to assess whether it is cancerous or not
What are the next steps once breast cancer has been identified via the biopsy?
- Masectomy OR lumpectomy to remove the tumor with incisions above and below the nipple parallel to the Langer lines to minimize scarring 2. Removal and biopsy of axillary lymph nodes with or without axillary incision (depending on whether masectomy or lumpectomy was performed) to test for metastasis 3. Surgical repair after radical masectomy
Which 2 nerves are very important to preserve during a masectomy?
- Long thoracic nerve, which controls serratus anterior2. Thoracodorsal nerve which controls latissimus dorsa
How do surgeons performing masectomies or lumpectomies find the lymph nodes to remove?
Lymph mapping using an injection of dye in the breast where the tumor was which will travel to the proximal lymph nodes to the tumor