Anatomy- Head And Neck Development Flashcards

1
Q

Gastrulaation three layers

A
  • ectoderm: epidermis, nervous system
  • endoderm: respiratory, digestive
  • mesoderm: MSK, dermis, ardiovascular
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2
Q

Promitrive streak/node

A
  • first sign of gastrulation, epiblast cell moveement inward -> becomes the three layers
  • diminishes after 4 weeks and becomes sacrum and coccyx
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3
Q

Notochord

A
  • triggers neural plate

- goes underneath ectoderm and sends out signal to it to become neural tissue

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4
Q
  • neural plate
A
  • thickening of ectoerm, CNS
  • also signalled by notchord - becomes neural groove - will become brain + spinal chord
  • neural crest cells: from ectoderm, nerves (cranials) and connective tissue, muscle, dermis
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5
Q

Cranium: foetal stage

A
  • base bones: complex, chunky cranium from cartilaginous origin
  • cranium flat bones from mesenchyme origine. Joined by sutures called fontanelles - molding during childbirth
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6
Q

Cranium: newborn

A
  • cranium round and large (thin)

- face small because jaw and sinuses have not developped

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7
Q

Cranium: postnatal

A
  • growth of cranium continues to 16 yo and then thickens until early 20
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8
Q

Clinical issues with cranium

A
  • acrania: cranium absent - death
  • craniosysnotosis: prenatal closure of sutures - in particular sagital suture
  • holoprosencephaly: single feature, cerebrum (single frontal lobe, cyclopia, single nostril….)
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9
Q

Pharyngeal arches

A
  • four main ones
  • 5/6 rudimentary
  • arches support walls of pharync
  • componentsL mesenchyme core, ectoderm, endoderm
  • arch has artery, cartilage, muscle, nerves
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10
Q

1st pharyngeal arch:

  • skeleton
  • muscle
  • nerve
A
  • skeleton: incus, malleus, maxilla, zygomatic, vomer, mandible, temporal
  • muscle: mastication, mylohyoid, anterior digastric, tensor tympani, TVP
  • nerve: trigeminal
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11
Q

2nd pharyngeal arch

  • skeleton
  • muscle
  • nerve
A
  • skeleton: stapes, styloid process, hyoid
  • muscle: facial expression, stylohyoid, posterior digastric, stapedius
  • nerve: facial
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12
Q

3rd pharyngeal arch

  • skeleton
  • muscle
  • nerve
A
  • skeleton: hyoid
  • muscle: stylopharyngeus
  • nerve: glossopharyngeal
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13
Q

4th/6th pharyngeal arch

  • skeleton
  • muscle
  • nerve
A
  • skeleton: laryngeal cartilages
  • muscle: LVP, palatoglossus, palatopharyngeus, pharyngeal constrictors, laryngeal
  • nerve: X
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14
Q

Pharyngeal pouches: four internal diverticula

A
  • 1st: tympanic cavity, auditory tube
  • 2nd: tonsillar fossa, palatine tonsil
  • 3rd, 4th: parathyroid gland, thymus
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15
Q

Pharyngeal grooves

A
  • four external clefts

1st: external acoustic meatus
- all the others obliterate

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16
Q

Pharyngeal membrane

A
  • one floor of grooves

- gives the tympanic membrane

17
Q

Clinical issues concerning the pharyngeal apparatus

A
  • pharyngeal fistula/sinus = cysts (2nd groove)

- 1st arch syndrome: eyes, ears, jaw, palate (neural crest cells)

18
Q

Thyroid gland development

A
  • 1st endocrine gland to develop (4-7 weeks): thickening in pharynx
  • descends in neck from tongue: foramen caecum
  • connected to tongue via thyroglossal duct around 7 week
19
Q

Clinical issues with thyroid gland development

A
  • thyroglossal duct and cysts

- ectopic thryoid gland

20
Q

Palate development

A
  • 1st median palatal process: anterior maxilla

- 2nd lateral palatal process: primordial hard/soft palate, maxillary prominences, septum from nasal prominences

21
Q

Clinical issues with palate development

A
  • cleft lip/palate: common anomalies
  • cleft lip: lips, nostril, maxilla: primary palate issue. Can be unilateral or bilateral
  • cleft palate: with or without a cleft lip: hard to soft palate/uvula, 2nd palate issue (no fuse maxillary)