Anatomy Exam #2 Flashcards
Sclerotome give rise to
Bones, cartilage, and tendon
Myotome give rise to
Muscles
Dermatome give rise to
Dermis of skin
Loose Connective Tissue Examples
lamina propria beneath epithelial lining of digestive tract
Dense Irregular Connective Tissue
dermis of skin, organ capsules, submucosa layer of digestive tract
Dense regular connective tissue
ligaments, tendons, aponeuroses, corneal stroma
Mesenchyme is the origin of ?
- origin of all connective tissue
- develops mainly from mesoderm
Mucoid Connective Tissue
matrix of the fetal umbilical cord
Reticular Connective Tissue
bone marrow, liver, pancreas, adrenal gland, all lymphoid organs except the thymus
Hurler’s syndrome
Lysosomal storage disease
gargoyle disease
Ehlers-Danlos syndrome
- rubberman syndrome
- Major symptoms include joint hypermobility, cutaneous laxity (i.e., stretchy skin), abnormal scar formation, vascular rupture
Marfan syndrome
- Patients tend to be tall, with long and thin limbs, long fingers (and toes), can suffer from scoliosis
- abe lincoln
Scleroderma
- Thickening of skin
- Essentially, dysregulation of fibroblasts and myofibroblasts leads to excessive collagen deposition, causing fibrosis
Osteogenesis imperfecta
- irregular bone formation
- the middle character
Scurvy
- Vitamin C deficiency
- Symptoms include bleeding gums, loose teeth, tooth loss, poor wound healing, edema
Psoriasis
is a disease characterized by patchy lesions caused by greater keratinocyte proliferation in the stratum basale and stratum spinosum and an accelerated cell cycle
Layers of skin
stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale, dermis
Platelets function
Clotting, vessel wall repair
Erythrocytes Function
O2 & CO2 transport
Leukocytes
immune response
Babesiosis
Depressed RBC and platelet counts that is a parasite that passes by ticks
eosinophils
- Elevated levels indicates parasitic infection
- Major contributor to inflammatory response
- Major contributor to allergies – dermatitis, rheumatoid arthritis, reflux esophagitis, asthma
neutrophils aka neutrocytes
- Most abundant WBC
- “First responders”
- Phagocytose bacteria (other anti-microbial actions)
- Neutropenia can indicate aplastic anemia, leukemia, chemotherapy
- Neutropenia increases risk of infection
basophils
- Involved in inflammatory response
- Deviations from normal count difficult to detect because baseline/normal count is already very low
mast cells
- Involved in parasite response, angiogenesis, wound healing, inflammation
- Implicated in allergic response and anaphylaxis
lymphocytes
Primary role: identification of self vs non-self
memory cells
These cells “remember” prior encounters with pathogens and tumors which facilitates faster and more effective immune response
Where are monocytes held and what can happen if this organ is damaged?
- held in the spleen and are released when an infections occurs
- if spleen is damaged, at risk for infection
Erythrocytes
Red blood cells
Sickle-cell disease
Point mutation that turns a hemoglobin A into a hemoglobin S – HbS or Hb-S
porphyria
- Result from defective heme
- Symptoms in some types include blistering after sunlight exposure
- Symptoms can be mitigated by the ingestion of blood
From which skeletal locations do we harvest hematopoietic marrow?
Iliac crest
Leukemia
- Pathological proliferation of bone marrow stem cells
- Diagnosis: repeated CBCs with elevated WBC counts
Polycythemia
- Overproduction of RBCs
- Manifests as abnormal thromboses
The median nerve innervates what muscles?
3 thenar muscles (recurrent branch) and 1,2 lumbricals
Main artery to superficial palmar arch
ulnar artery
Main artery to deep palmer arch
radial artery (lies under anatomical snuff box and passes between adductor policis head)
muscle that runs over the hypothenar muscles and function?
palmaris brevis covers/protects ulnar nerve and artery
Dorsal interossei muscle action?
DAB abduction (connect to digit 1,4,5)
Palmar interossei muscle action
PAD adduction (connect to digits 2-4)
Lumbrical action along with dorsal and palmar interossei
- Flex the fingers at the metacarpophalangeal joints and extend the interphalangeal joints
- all connect to extensor expansion
Superficial radial nerve innervates what in the hands?
Lateral two-thirds of the dorsum of the hand
DR. CUMAB
Wrist Drop: radial nerve
Claw Hand: ulnar nerve
Ape Hand and Benediction hand: median nerve
Deep branch of the Ulnar Nerve innervates?
- Three hypothenar muscles
- Medial two lumbricals
- Adductor pollicis
- Deep head of the FPB
- All palmar and dorsal interossei
Laceration of the median nerve at the wrist results inn
- paralysis of the thenar muscles and the first two lumbricals:
- opposition of the thumb is not possible
- fine control movements of the 2nd and 3rd digits are impaired
- sensation is also lost over the thumb and adjacent two and a half fingers
Radial Nerver innervation
brachioradialis
ECRL
Deep Branch of Radial
ECRB
Supinator
Posterior interosseous nerve
everything but ECRL, ECRL, supinator, brachioradialis
Tennis Elbow
-Extensor Carpi Radialis Brevis (ECRB)
-Caused from repetitive or overuse use of superficial extensor muscles
Pain over lateral epicondyle that radiates down the posterior surface of the forearm
Golfer’s Elbow
felt on the medial epicondyle
Repetitive or overuse of flexor muscles
Mallet/Baseball Finger
Hyperextension of a long extensor tendon at the distal interphalangeal joint
Zonula adherens
Cell to cell
Actin
Cadherin
Desmone
Cell to cel
Intermediate
Catherin
Focal Contact
Cell to matrix
actin
integrin
Hemidesmosome
cell to matrix
intermediate
integrin
Microvilli location
intestin kidneys
Stereocilia are and location
long microvilli
epididymis (absorption) and ear cochlea (sensory receptors)
Cilia action and location
transport material (beating dynein) respiratory tract, oviducts
Zonula Occludens (tight junction) location
stomach and kidney
coracoid-acromial arch
coracoid process, coracoacromial lig, and acromion
Fall on shoulder
dislocate acromioclavicular joint with coracolavicular lig rupture
Fall on elbow
dislocate acromioclavicular joint only
Dislocating shoulder can risk rupture of what arteries and nerves
ant/post. circumflex humeral a, axillary/radial nerve
Subluxation and dislocation of radial head
anular ligament
Colles’ fracture
fracture distal end of radius
Quadricep Muscles
Vastus lateralis, intermedius, medialis, rectus femoris
Innervation: Femoral nerve
Action: Extend at knee
Obturator Externus innervation
obturator nerve
Femoral Sheath includes and excludes
includes: femoral artery, vein, and ingiuneal lymph
excludes: femoral nerve
Pes Anserinus and insertion
- semitendinosus, gracilis, satoris
- sup part of medial surface of tibia
Obturator nerve innervates
Adductor longus, brevis, magnus (adductor part), obturator externus, gracilis
Obturator internus, superior gemelli innervation
nerve to obturator internus
Quadratus femoris and inferior gemelli innervation
nerve to quadrates femoris
Superior Gluteal nerve innervates
G med, G min, and TENSOR FASCIA LATAE
Intragluteal injections
Superolateral quadrant
Superior Gluteal Nerve injury
- loss function of G med, G min
- paralyzed hip in go up
- Pos. Trendelenburg Test
Week 4
curved, with upper limb buds
Week 5
hand and foot plates
Week 6
fingers, toes, ears, or at least their primordia are clear
Week 7
arm is longer, bent at elbow, fingers distinct but likely webbed
Week 8
Fingers should be free, toes should be distinct but likely webbed – tail present
Collagen type IV
Gives structure to basal lamina
Blood supply to posterior thigh
- perforating branch or medial circumflex femoral
- BICEP FEMORIS: same + inf. gluteal a
Innervation to posterior thigh
- All tibial nerve
- Except BICEP FEMORIS (SHORT HEAD): common fibular
Hamstring Muscles attachment
Ischial Tuberosity [except bicep femoris (shorted): linea aspera]
Vein and nerve that run posterior to gastrocnemius?
medial sural->sural nerve, and small saphenous vein