Anatomy and physiology- Lymphatic system Flashcards

1
Q

what is the lymphatic system?

A

Anetwork of delicate tubes throughout the body that consists of lymph vessels, ducts, nodes, and other tissues.

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2
Q

What are the main roles of the lymphatic system?

A

managing the fluid levels in the body

reacting to bacteria

dealing with cancer cells

dealing with cell waste that otherwise would result in disease

absorbing some of the fats in our diet from the intestine

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3
Q

What do the lymph nodes and other lymphatic structures like the spleen and thymus hold?

A

special white blood cells called lymphocytes. These can rapidly multiply and release antibodies in response to bacteria, viruses, and a range of other stimuli from dead or dying cells and abnormally behaving cells such as cancer cells.

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4
Q

What is lymph formed from

A

plasma

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5
Q

what are thesmaller lymphatic vessels called?

A

They take up the fluids from the tissue, and are called lymph capillaries.

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6
Q

What do thelarger lymphatic vessels have?

A

Muscles in their walls which helps them gently and slowly pulsate. These larger lymphatic vessels also have valves that stop the lymph flowing back the wrong way.

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7
Q

what is the thymus gland?

A

A gland that forms part of the immune system. It is situated in the upper part of the chest, behind the breastbone

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8
Q

What does the thymus do?

A

The thymus produces and secretesthymosin, a hormone necessary for T cell development and production

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9
Q

What does the thymus do?

A

The thymus produces and secretesthymosin, a hormone necessary for T cell development and production

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10
Q

what are the two types of lymphocytes?

A

T cells - mature in theThymus

B cells - mature in theBone marrow

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11
Q

T and B cells need to do what to fight infection?

A

Both T Cells and B Cells are types of lymphocytes found in the body and must work together to fight infection

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12
Q

How do T and B cells work together?

A

T lymphocytes act to remove infected cells by killing them directly and are important in also killing cancer cells. B lymphocytes secrete chemicals called antibodies into the blood, and these help to remove or kill the invading pathogens. Once activated B cells are calledplasma cellsand are a short-livedantibody-producingcells releasing a large amount of antibody into the circulation.

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13
Q

what are the the are 5 types of white blood cell?

A
  1. Lymphocyte
  2. Monocytes
  3. Eosinophils
  4. Basophils
  5. Neutrophils
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14
Q

what do Lymphocytes do?

A

They are responsible for directly killing many foreign invaders (e.g.viruses) and they also produce the antibodies that “remember” an infection and stand ready in case your body should be exposed again.

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15
Q

what do Monocytes do?

A

they are thegarbage trucksof the immune system and their most important function is to migrate into tissues and clean up dead cells.

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16
Q

what do Eosinophils do?

A

they play an important role in fighting off disease and are very important in responding to infections withparasites(such as worms)

17
Q

what do Basophils do?

A

they are important in mounting a non-specific immune response to pathogens, they release histamine among other chemicals that stimulates the rest of the immune system into action - they are raised in certainallergic reactions.

18
Q

what do Neutrophils do?

A

Roughly half of white blood cells are neutrophils. Neutrophils are usually the first cells of the immune system to respond in response to an invader such as abacteria. As first responders, they also send out signals alerting other cells in the immune system to respond to the scene.

19
Q

Bone marrow is the spongy material at the centre of some of our bones, what cells does it make?

A

It makes all the new blood cells we need, including both red blood cells and the different white blood cells

20
Q

what do Red blood cells do?

A

Carry oxygen from the lungs to tissues around the body and then remove carbon dioxide from the tissues for transporting back to the lungs.

21
Q

what are Platelets?

A

Platelets are tiny blood cells that help your body form clots to stop bleeding.

22
Q

how do phagocytosis break down/kill a pathogen

A

Phagocytes are attracted to pathogens in the blood and bind to them – they then surround the pathogens and engulf them (like an amoeba).

23
Q

how do Lymphocytes kill a pathogen?

A

Lymphocytes recognise proteins on the surface of pathogens called antigens. Lymphocytes detect that these are foreign and do not naturally occur within your body and so produce antibodies.

The antibodies cause pathogens to stick together and then make it easier for phagocytes to engulf them. Some antibodies can destroy pathogens directly.

24
Q

what size and shape is a lymph node?

A

They are shaped like a bean and usually less than 1 cm long.

25
Q

where can lymph nodes be found?

A

In the neck (cervical nodes)

Under the arm (axillary nodes)

In the groin (inguinal nodes)

In the centre of the chest between the lungs (mediastinal nodes)

In the abdomen (mesenteric nodes

26
Q

what is the spleen home to?

A
  1. Cells called ‘macrophages
  2. Lymphocytes
  3. Platelets
27
Q

what are four spleen function

A
  1. store lymphocytes
  2. Filter and remove old damaged red blood cells from the circulation
  3. Act as a blood reservoir in times of shock and haemorrhage
  4. Preserves iron when old red cells have been broken down.
28
Q

what are the two different tissues in the spleen?

A

Red pulp

white pulp

29
Q

what makes up red pulp?

A

Contains venous sinuses (cavities filled with blood), and splenic cords (connective tissues containing red blood cells and white blood cells).

30
Q

what makes up white pulp?

A

Mostly consists of immune cells (T cells and B cells).

31
Q

The immune system works within our body to keep us free of infection and disease. what It is made up of?

A

Physical barriers

Immune cells

Proteins

32
Q

what do physical barriers do?

A

A physical barrier is made up of the mucosa- e.g eye, nose, mouth and bowel that are also protected by fluids that wash the mucosa

33
Q

how do immune cells protect against infections?

A

The 5 different white blood cell types.

34
Q

how do proteins protect against infection?

A

Antibodies (they are also known as ‘immunoglobulins’) can stick to other proteins called ‘antigens’ on the surface of organisms (such as bacteria and viruses) and can kill bacteria.

35
Q

Name the main organs / glands of the lymphatic system

A

bone marrow, spleen, thymus gland, lymph nodes, and the tonsils

36
Q

Briefly describe the movement of lymph through the body

A

Lymphatic vessels collect and filter lymph (at the nodes) as it continues to move toward larger vessels called collecting ducts.

37
Q

Name the 2 main lymphatic ducts in the thoracic area

A

theright lymphatic ductand thethoracic duct

38
Q

Name 3 main areas where lymph nodes are situated in the body

A

neck, armpit and groin