Anatomy Flashcards
What is a collection of nerve cell bodies in the CNS called?
Nucleus
What is a collection of nerve cell bodies in the PNS called?
Ganglion
What do dendrites do?
Transport signal towards cell body
What do axons do?
Transport signals away from the cell body
What cells produce the myelin sheath in the PNS?
Schwaan cells
What cells produce the myelin sheath in the CNS?
Oligodendrocytes
What neuronss are usually motor polar?
Motor efferent
Skeletal muscles
What neurons are usually unipolar?
Sensory afferent
Where is the cell body located in unipolar neurons?
PNS
Where is the cell body located in multipolar neurons?
CNS
What are nerves?
Bundles of neurons surrounded by connective tissue and blood vessels.
What are the two types of nerves?
Single or mixed modality
What does it mean to be a mixed modality nerve?
Mixture of somatic motor somatic sensory and sympathetic grouped together.
Sympathetic outflow is…
Thoracolumbar T1 to L2
Where are sympathetic cell bodies located ?
Lateral Horn
Upon leaving the spinal column where do the sympathetic neurons pass?
Anterior Rami
Spinal Nerve
White Rami
Sympathetic Trunk
What are the four routes presynaptic axons take in the sympathetic trunk?
- Ascend then synapse
- Synapse at level of entry
- Descend and then synapse
- Pass through sympathetic trunk to synapse at prevertebral ganglia.
If a sympathetic nerve synapses within the sympathetic trunk it…
Synapses at paravertebral ganglia
If a sympathetic nerve synapses outside of the sympathetic trunk it….
Synapses at prevertebral ganglia
What make up spinal nerves?
Somatic motor sensory and sympathetic neurones
In order to supply abdominopelvic organs where do sympathetic neurones synapse?
Prevertebral ganglia
List the 4 Prevertebral ganglia associated with the abdominopelvic organs?
Celiac Ganglion
Aorticorenal ganglion
Superior Mesenteric Ganglion
Inferior Mesenteric Ganglion
Roughly where does the celiac ganglion innovate?
Foregut
Roughly where does the aorticorenal ganglion innovate?
Kidneys
Roughly where does the SMG innovate?
Midgut
Roughly where does the IMG innovate?
Hindgut
Pelvic and Perineal plexus
Where do sympathetic neurones directly synapse onto the target organ?
Adrenal Medulla on the kidney
Parasympathetic output is….
Craniosacral
What cranial nerves are parasympathetic?
CN III Oculomotor
CN VII Facial
CN IX Glossopharyngeal
CN X Vagus
At 4 weeks what are the three layers that make up the neuro system?
Prosencephalon
Mesencephalon
Rhombencephalon
What does the prosencephalon develop into?
Telencephalon
Diencephalon
What does the telencephalon become?
Cerebral Hemisphere
What does the Diencephalon become?
Thalamus and hypothalamus
What does the Mesencephalon become in the developed brain?
Midbrain pons and medula
What does the rhombencephalon develop into?
Metencephalon
Mylencephalon
The mesencephalon and mylencephalon form which parts of the fully developed brain?
Midbrain
Pons
What are the four types of glial cells
Atrocytes
Oligodendrocytes
Microglia
Ependymal
Astrocytes
Star shaped
Maintain the Blood Brain Barrier
Oligodendrocytes
Produce myelin sheath within the CNS
Microglia
Similar function to macrophages
Found in an inactive state
Ependymal
Ciliated cuboidal epithelium that line the ventricles
Not the BBB
What is a gyrus?
Lumps
What is a fissure?
A deep invagination
What are sulci?
Furrows/ Grooves
Within the brain what is grey matter?
Lines the outside
Huge number of neurones cell bodies synapses etc
Within the brain what is the white matter?
Medullary centre
Axons mostly myelinated
What forms the thalamus and why is this interesting?
Grey matter
Located within the brain
Think the brain is a folded tube
What is different about the spinal chord?
Grey matter forms the centre and is surrounded by white matter.
What separates the parietal and frontal lobes?
Central sulcus
What separates the parietal and occipital lobes?
Parieto occipital sulcus
What separates the occipital from the cerebelum?
Preoccipital notch
What are the three meningeal layers?
Dura Matter
Arachnoid matter
Pia Matter
Dura Matter
Tough outer layer
Arachnoid Matter
Middle layer
Sub arachnoid space contains CSF
Pia Matter
Directly attached to surface of the brain
Shiny appearance as few cells thick
How many ventricles are there?
4
2 x lateral
3rd
4th
What connects the two lateral and the third ventricles?
Interventricular foramen
What connects the third to the fourth ventricle?
Cerebral aqueduct
What two plexus make up the enteric nervous system?
Myenteric plexus
Submucosal plexus
Where would you find the enteric nervous system?
Digestive system
Where would you find the myenteric plexus?
Between the longitudinal and circular smooth muscle layers
Where would you find the submucosal plexus?
Located within the mucosa
What major blood vessel supplies the anterior portion of the brain?
Interior carotid arteries
Upon entering the brain what vessels do the internal carotids form?
Anterior Cerebral arteries
Middle Cerebral arteries
The two intervertebral arteries combine in the brain to from what?
Basilar arteries
What does the basilar artery form?
Posterior cerebral arteries
What small vessels connect the anterior of the circle of willis to the posterior?
Posterior communicating artery
How are sinuses formed?
Separation of the two layers of dura matter.
What are the two layers of dura?
Periosteal faces the bone
Meningeal
What vessels drains blood from the brain?
Cerebral veins
The cerebral veins empty into…
Superior or inferior sagittal sinus
Where is the confluence of the two sinuses?
Midline of the internal occipital protuberance
Where do the sinuses empty into?
Internal jugular vein
In which meningeal layer does the circle of willis sit within?
Sub arachnoid space
Its bathed in CSF
How many spinal nerves are there?
31 8 Cervical 12 Thorasic 5 Lumbar 5 Sacral 1 Coccygeal
Why are there 8 cervical nerves but only 7 vertebrae?
Cervical nerves originate superiorly to the vertebrae and then at 7 they start originating inferiorly.
Where is the only spinal nerves are found?
Within the intervertebral foramina
Posterior Rootlets have what modality?
Sensory
Anterior rootlets have what modality?
Motor and sympathetic
What does the posterior rami supply?
Posterior body wall
What does the anterior rami supply?
Anterolateral body wall
Spinal meninges are continuous with cranial? T/F
True pass through the foramen magnum
What suspends the spinal canal within the spine?
Denticulate ligaments - formed of pial and arachnoid tissue
White matter within the spinal chord
Longitudianlly orientated nerve fibres, glial cells and blood vessels.
Grey matter within the spinal chord
Neuronal cell process synapses glial cells and blood vessels.
What forms the columns and what divides them?
White matter
Horns of grey matter divide it up
How do posterior horns help to determine the orientation of a specimen?
Posterior horns extend to almost the border. They are much longer.
What differentiates the spinal column between T1 - L2?
They have a lateral horn made up of preganglionic sympathetic neurones
What artery supplies the anterior portion of the spine running down the length anteriorly?
Anterior spinal artery
What arteries supply the posterior portion of the spine?
2 x posterior spinal artery
What spinal arteries are derived from intercostal or lumbar arteries?
Segmental arteries
What arteries supply the anterior and posterior rootlets?
Radicular
What ligament connects the tips of the spinous process ?
Supraspinous Ligaments
Which ligament connects the inferior and superior surfaces of adjacent spinous process?
Interspinous Ligaments
Which ligament prevents over extension of the spine?
Anterior Longitudinal Ligament
What is the function of the anterior longitudinal ligament?
Broad and strong it helps support the discs
Which ligament prevents over flexion of the spine?
Posterior Longitudinal Ligament
What is the strong outer layer of the intervertebral discs?
Annulous Firbrous
What is the softer inner layer that cushions the vertebrae?
Nucleus Pulposus
Where do synovial joints between adjacent vertebrae attach?
Superior Articular Process
Where do the ribs articulate with the vertebrae?
Transverse Process
What are three regions of the cerebellum?
Anterior - smaller
Posterior - larger
Floculonodular - runs interiorly
What attaches the cerebellum to the brain stem?
Three peduncles
Superior
Middle - largest
Inferior
Small bumps on the cerebellum are referred to as what?
Folia
What are the small cuts into the surface of the cerebellum called?
Sulcus
What is the function of the floculonodular node?
Coordinates the input from the vestibular system
What are the three cell layers of the grey matter within the cerebellum?
Molecular
Purkinje
Granule
What is the job of the Purkinje layer within the grey mater of the cerebellum?
Transport afferent inputs
What is the Arbor Vitea?
White matter of the cerebellum
Where is the grey matter located in the cerebellum?
Superficially and the dentate nuclei located deep to the arbor vitea.
Where does the spinal chord end?
Conus Medullaris us found roughly L1-L2