Anatomic Pathology - Swine cases Flashcards
This kidney is from a 2-day-old foal that died after a short course of depression, weakness, and hypothermia. a. Describe the gross lesions.
multifocal white pinpoint lesions throughout
likely cause of multifocal white lesions throughout kidney in 2-day old foal
indicate speticemia: -Actinobacillus equuli (white lesions are mass of bacteria)
18-month-old filly with an acute onset of edema of the limbs and head, fever, and depression.
There are petechial hemorrhages on the serosal surface of the intestine and in the subcutis.
Describe two distinct pathogeneses for these lesions, and the causes of each.
- thrombocytopenia dt DIC, BM dz, or ITP
2. Vascular injury resulting from EVA or PH (Ag-Ab complexes from Strep equi)
Lung from a 5-month-fold foal with an acute onset of dyspnea and fever. The second photo is a cross-section of the cranioventral lung.
a. Describe the gross lesions.
Lesions affect the cranioventral 50 percent of the lung. the lung is consolidated and reddened, and the cut section reveals numerous coalescing focal lesions up to 1-cm-diameter, which are white and caseating
most likely cause of CV pneumonia in 5month old foal
R equi
how confirm dx of R equi
bact culture, histo of tissue, or cyto of impression smear
R equi can cause other lesions:
- colonic lesions accompanied by granulomatous lymphadenitis with foci of necrosis
- polyarthritis (septic or non-septic)
Blood fills the pericardial sac in this case and track along the soft tissues adjacent to the aorta. What are the causes of hemopericardium in any species, and in racing horses in particular?
racing: ruptured aorta b/c high P during exercise
or: truama or penetrating injury, ruptured HSA (dogs), idiopathic chronic hemopericardium (dogs)
What are other common causes of sudden death in horses?
- extensive intrapulm hemorrhage
- arrythmia
- lightning strike
- anaphylaxis, elctrocutioan, gunshot, drowning, intestinal accidend, botulism, speticemia, heat stroke, toxicity
do most toxins= sudden death?
no except jap yew, organophos, cardiac glycosides
can rely on singed hair for lightning strikes?
no
common causes of non-infect EQ abortion:
twins, torsion of umb cord, placental insuff, body pregnancy, premature placental sep, malformation
infectious causes of equine abortion
EHV-1 common
Lepto, EVA not common
what lesions present
liver contains multiple pinpoint white areas of necrosis.
if have multifocal liver necrosis adn lungs are diffusely rubbery and firm with 1-3mm foci in EQ-
dx and confirm:
EHV-1
confirm with histo- intranuclear inclusion bodies
can vaccinated mares still abort with EHV-1?
yes, reduces P but doesn’t eliminate it
if see green area in medulla of kidney of EQ think:
NSAID toxicity
why NSAID tox in medulla?
prostaglandins import in mnting renal medullary blood flow adn NSAID inhibit cyclooxygenase
other manifestations of NSAID tox in horseL
- right dorsal colon lesions
- fundic stomach ulcers
