Anaphylactic Shock

Question 1

What type of hypersensitive reaction is anaphylactic shock

Answer 1

IgE mediated
*airway risk (angioedema, tongue, laryngeal edema)
*need early intubation

Question 2

What is the dosage of epi given to children and adults

Answer 2

Children
*0.01mg/kg IM mid outer thigh
Adults
*0.3-0.5mg IM mid outer thigh

*no absolute CI to epi in the setting of anaphylaxis

Question 3

What is given if refractory to IM epi

Answer 3

Iv infusion
1. 0.1mcg/kg/min
*titrate the dose contrinously according to blood pressure, cardiac rate and function and oxygenation

Question 4

What is given during anaphylactic shock

Answer 4

1. IV fluid adminsitration-crystalloid (bolus)
2. Bronchodilator-albuterol by nebulizer
3. Histamine Blockade
4. Glucocorticoid

Question 5

What histamine block is given for anaphylactic shock

Answer 5

H1
*diphenhydramine
H2
*pepcid

Question 6

What type of glucocorticoid is given during anaphylactic shock

Answer 6

Methylprednisolone

Question 7

If a patient is on a beta blocker what are they given

Answer 7

Glucagon

Question 8

What are the signs of anaphylactic shock

Answer 8

1. Pruritus
2. Hives
3. Angioedma
4. Distress
5. Lump in throat