Anaesthetics Flashcards

1
Q

what is nociceptive pain?

A

normal response to perceived or actual injury to the tissues, occurs in normally functioning nervous system, leads to perception of pain

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2
Q

what are nociceptors?

A

Agamma and C fibre free endings

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3
Q

what is chronic pain described as?

A

over 12 weeks or beyond normal course of how long it should last, can be caused by cancer

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4
Q

what do C fibres transmit

A

dull pain

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5
Q

which tracts carry nociception?

A

spinothalamic

spinoreticular

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6
Q

how does tissue injury cause pain?

A

directly-inflammation and damage to surrounding tissue
indirectly-damage>membrane lipids broken down by phospholipase A2>arachidonic acid, COX changes it to prostaglandins> stimulate nociceptors

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7
Q

chronic pain types?

A
cancer
complex regional pain syndrome
MSK
persistant post op
diffuse idiopathic
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8
Q

where is pain signalled to

A

pons and midbrain (periaqueductal grey, nucleus raphe magnus and locus coerleus) and the thalamus>sensory cortex

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9
Q

where do we become aware of pain?

A

when it reaches somatosensory and anterior cingulate cortices

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10
Q

which laminae are pain signals transmitted to?

A

I and II

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