Anaemia Flashcards

1
Q

What is anaemia

A

A decreased number of RBC in the blood

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2
Q

HB in men (anaemia)

A

<130

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3
Q

HB in women (anaemia)

A

<120, <110 in pregnancy

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4
Q

Common causes of anaemia

A

-Diet insufficiencies, systemic disease,
-primary bone marrow disorders,
-autoimmune conditions,
-primary abnormalities of erythrocytes
-blood loss

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5
Q

types of WBC

A
  • Lymphocyte
  • Monocyte
  • Eosinophil
  • Basophil
    -Neutrophil
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6
Q

Immature RBC called

A

reticulocyte

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7
Q

Mature RBC lifespan

A

120d

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8
Q

Primary function of the erythrocyte

A

Fight infection
Aid blood clotting
transport b12
transport Co2 and O2

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9
Q

how many oxygen molecules can one rbc carry

A

4

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10
Q

Clinical signs of anaemia

A

Fatigue
Dizziness
Headaches
SOB
Lethagy/weakness
Compensatory tachycardia
Bounding pulse/palpitations

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11
Q

Visual clinical exam of anaemia - skin

A

Pale palmar creases
Dermatitis
Pallor
Jaundice
leg ulcers, peripheral neuropathy

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12
Q

Visual clinical exam of anaemia - cardiac

A

Palpitations, Pitting oedema, New onset or worsening angina

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13
Q

Visual clinical exam of anaemia - hands

A

Clubbing, nail discoloration, koilonychia

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14
Q

Visual clinical exam of anaemia - abdo

A

Splenomegaly

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15
Q

Visual clinical exam of anaemia - mouth

A

Glossitis
Angular Stomatitis

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16
Q

3 primary causes of anaemia

A

Reduced production of rbc
haemolysis
haemorrhage

17
Q

Reduced production of RBC Causes

A

nutrient deficiency
hormone deficiency
disease or other conditions

18
Q

Haemolysis is

A

excessive rbc destruction, often hereditory

19
Q

haemorrhage caused by

A

excessive blood loss
GI ulcers
Menstrual heavy loss
OD of aspirin
etc

20
Q

MCV stands for

A

mean cell volume

21
Q

MCV tests what

A

average size of rbc

22
Q

MCV 80-100

A

normocytic

23
Q

MCV <80

A

Microcytic

24
Q

MCV >100

A

Macrocytic

25
Q

MCH stands for

A

mean cell haemoglobin

26
Q

MCH means

A

Average concentration of haemoglobin in RBC,
the colour of the cells

27
Q

low MCH =

A

hypochromic

28
Q

Microcytic, hypochromic anaemias cause

A

IDA, anaemia of chronic disorders, thalassaemia, sideroblastic anaemia

29
Q

Macrocytic, normochromic anaemia cause

A

B12 deficiency, folate deficiency, alcohol excess, liver disease, thyroid disease

30
Q

normocytic, normochromic anaemia causes

A

anaemia of chronic disease, acute blood loss, early iron deficiency, anaemia of renal failure

31
Q

a low reticulocyte count would suggest problems with ?

A

bone marrow

32
Q

reticulocyte is an index of what

A

the bone marrow health and response to anaemia

33
Q

reticulocyte helps differentiate what

A

an anaemia that occurs because of bone marrow failure vs haemorrhage or haemolysis

34
Q
A