Alzeimers Drugs Flashcards
1
Q
donepezil (Aricept)
rivatigmine (Elexon)
A
class: cholinesterase inhibitor
MOA: prevents the breakdown of ACh acetylcholinesterase
helps with short-term improvement of symptoms
AE: bradycardia
bronchoconstriction
cholinergic effects
rivastigmine : reapply patch in different area
2
Q
memantine (Namenda)
A
Class: NMDA receptor antagonist
MOA: modulates the effects of glutamate on NMDA receptors
Uses: moderate to severe Alzheimers
AE: confusion, constipation, alkalinized urine can decrease urinal secretion
