Alpha blockers Flashcards
1
Q
What is it indicated for?
A
Treatment of lower urinary tract symptoms in benign prostatic enlargement
2
Q
How does it work?
A
It inhibits α1-adrenoceptors, causing vasodilation and reduction in BP
It also reduces resistance to urine outflow from the bladder
3
Q
What are the side effects of this drug class?
A
Postural hypotension
Dizziness
Syncope
This particularly occurs after the first dose
4
Q
What are the names of commonly used drugs in this class?
A
Tamsulosin
Doxazosin
Alfuzosin
5
Q
What are the interactions of this drug class?
A
Antihypertensive drugs cause BP lowering
Phosphodiesterase type 5 (PDE-5) inhibitors (sildenafil)
6
Q
What drug in this class is licenced for hypertension?
A
Doxazosin
