Aldosterone receptor antagonist (HF) Flashcards
1
Q
How is there aldosterone escape during ACEI therapy?
A
angiotensin 2 escape during ACEI
ang 2 causes aldosterone to rise
2
Q
What do they block?
A
blocks aldosterone receptors
3
Q
What good effects does decreasing aldosterone have?
A
dec PV
dec congestive symptoms
dec remodelling
4
Q
What are they used with?
A
ACEIs
beta blockers
diuretics
5
Q
UK licenced agents
A
spironolactone
eplerenone
6
Q
adverse effects
A
impotence and gynaecomastia (large breasts in men)
menstrual disorders and hirsutism (hair growth)
hyperkalaemia
