Aldosterone Hormone Flashcards

1
Q

Aldosterone main site of action in the kidneys?

A
  1. Collecting ducts
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2
Q

Aldosterone Mechanism of action in Principal Cells of the collecting duct?

A
  1. ⬆️Na K ATPase
  2. ⬆️Na+ reabsorption
  3. ⬆️K+ secretion
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3
Q

Aldosterone Mechanism of action in Intercalated Cells of the collecting duct?

A
  1. ⬆️H-ATPase
  2. ⬆️H+ secretion
  3. ⬆️HCO3- reabsorption
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4
Q

Change in pH with ⬆️Aldosterone ?

A
  1. ⬆️pH Metabolic Alkalosis
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5
Q

Changes in pH with ⬇️Aldosterone ?

A
  1. ⬇️pH Metabolic Acidosis
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6
Q

What are the short term regulators of Aldosterone ?

A
  1. Angiotensin II

2. K+ levels

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7
Q

Long term regulator of Aldosterone?

A
  1. RAAS
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8
Q

Afferent arteriole ⬆️ in volume leads to —— in Aldosterone levels?

A

⬇️Aldosterone

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9
Q

Afferent arteriole ⬇️ in volume leads to —— in Aldosterone levels?

A
  1. ⬇️Aldosterone
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10
Q

An ⬆️ in Na+ levels in Macula Densa leads to ___ in Aldosterone levels?

A
  1. ⬇️RAAS and ⬇️Aldosterone
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11
Q

An ⬇️ in Na+ levels in Macula Densa leads to ___ in Aldosterone levels?

A
  1. ⬆️RAAS and ⬆️Aldosterone
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12
Q

Other name for Primary Hyperaldosteronism?

A
  1. Conn’s Syndrome
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13
Q

Primary Hyperaldosteronism Etiology?

A
  1. Adrenal Adenoma

2. Bilateral Adrenal Hyperplasia

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14
Q

Main signs for Primary Hyperaldosteronism?

A
  1. Hypertension
  2. Hypokalemia
  3. Metabolic Alkalosis
  4. ⬇️Renin
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15
Q

Secondary Hyperaldosteronism main Etiology?

A

—HYPERTENSION—

  1. Bilateral Renal Stenosis
  2. Bilateral Renal Fibromuscular Hyperplasia

—HYPOTENSION—

  1. CHF
  2. Nephrotic Syndrome
  3. Hepatic Cirrhosis

BOTH HAVE ⬆️Renin

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