Alcohol (test 1) Flashcards

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1
Q

drinking guidelines for men

A
  • 15 drinks a week

- no more than 3 a day most days

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2
Q

drinking guidelines for women

A
  • 10 drinks a week

- no more than 2 a day most days

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3
Q

heavy drinking

A
  • drinking 5 or more drinks in one occasion

- 12 or more times over the past year

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4
Q

typical spike in drinking habits

A

18-24

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5
Q

Mac got your back campaign

A

education on a standard drink

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6
Q

BAC of intoxication

A

0.08

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7
Q

BAC to vomit, and trigger zone

A

0.15, trigger zone is Area Postrema

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8
Q

ethyl alcool

A
  • drinking alcohol

- smaller and can get into bloodstream easier

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9
Q

methyl alcohol

A

fuel and industrial solvents

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10
Q

isopropyl alcohol

A

rubbing alcohol

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11
Q

________ inhibitory neurotransmitters

A

increases

  • GABA
  • glycine
  • adenosine
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12
Q

________ excitatory neurotransmitters

A

decreases

  • glutamate
  • aspartate
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13
Q

too much firing of neurotransmitters may cause ________

A

seizures

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14
Q

glutamate with acute use

A
  • inhibition of glutamate transmission by reducing, decreasing the effectiveness of glutamate at the NMDA receptors
  • memory loss
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15
Q

glutamate with chronic use

A
  • increases the number of NMDA receptors in response to reduced glutamate activity
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16
Q

glutamate response in withdrawal

A

increased glutamate activity , brain damage

17
Q

GABA with acute use

A

enhances GABA induced Cl- influx

hyper polarization

18
Q

GABA with chromic use

A

neuro-adaptation compensates for initial GABA enhancing, contributes to appearance of tolerance and signs of withdrawal (seizures)

19
Q

dopamine with acute use

A

increase in transmission in meso-limbic tract (pleasure)

20
Q

dopamine with chronic use

A

reduced firing rate

drink more to chase the feeling of the original happy pleasure

21
Q

opioids response to withdrawal

A

negative affect

22
Q

opioids with acute use

A

increase in endogenous opioid synthesis and release (reinforcement)

23
Q

opioids with chronic use

A

neuro-adaptive decrease in endorphin levels (dysphoria)

24
Q

first ___% of alcohol absorbed in stomach

A

10%

25
Q

rest absorbed in what order ________

A

The intestines, bloodstream, then the liver

26
Q

how much can the body effectively metabolize

A

1 drink per hour

27
Q

symptoms of intoxication

A
  • relaxation
  • memory deficits
  • decreased social inhibition
  • decreased judgement
  • decreased coordination
  • impaired fine motor
  • delayed reaction time
28
Q

what factors can impact impairment

A
  • speed of consumption
  • food consumption
  • mixed with drugs
  • frequency of alcohol consumption
  • mood and physiological makeup
  • size, weight, sex
29
Q

male vs. females

A
  • alcohol dehydrogenase is 60% more active in genetic males

- leaving an increased percent of alcohol to be absorbed in the blood of women

30
Q

alcohol breakdown

A

alcohol broken down by alcohol dehydrogenase into acetaldehyde which is broken down by acetaldehyde dehydrogenase into acetic acid which is broken down by oxidation into CO2, H2O, energy

31
Q

Alcohol and dopamine neurons

A
  • causes increased firing of dopamine neurons
  • NOT increase in dopamine throughout the brain
  • dopamine increase in reward pathway
32
Q

alcohol induced brain damage

A
  • increased ventricle size from neuronal death

- decrease in axon health

33
Q

hierarchal organization

A

Higher levels of information processing control the more complex aspects of behaviour